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The Janus face of CaMKII: from memory consolidation to neurotoxic switch in Alzheimer's disease.

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第一作者： Luhong,Tang

第一单位： Department of Clinical Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, China.

作者： Luhong,Tang ^[1] ; Feng,Liu ^[2] ; Xuefei,Sun ^[3] ; Jiaoyan,Yang ^[1] ; Yifang,Liu ^[1] ; Xueting,Pan ^[1] ; Liying,Hao ^[4] ; Fan,Lou ^[5] ; Jingyang,Su ^[6]

作者单位： Department of Clinical Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, China. ^[1] Department of Endocrinology and Metabolism, The Fourth People's Hospital of Shenyang, China Medical University, Shenyang, 110000, China. ^[2] Department of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang, 110122, China. ^[3] Department of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang, 110122, China. lyhao@cmu.edu.cn. ^[4] Department of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, Liaoning, China. loufan1018@163.com.;Key Laboratory of Neurological Disease Big Data of Liaoning Province, Shenyang, 110001, Liaoning, China. loufan1018@163.com.;Shenyang Clinical Medical Research Center for Difficult and Serious Diseases of the Nervous System, Shenyang, 110001, Liaoning, China. loufan1018@163.com. ^[5] Department of Clinical Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, China. jysu@cmu.edu.cn. ^[6]

关键词 Alzheimer’s disease Ca2?/CaM-CaMKII Calcium dyshomeostasis Learning and memory function Synaptic plasticity