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Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling.

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第一作者： Agnese,Kocere

第一单位： Department of Pediatrics, Section of Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Department of Molecular Life Sciences, University of Zürich, Zürich, Switzerland.

作者： Agnese,Kocere ^[1] ; Elena,Chiavacci ^[2] ; Charlotte,Soneson ^[3] ; Seth T,Jacobson ^[4] ; Emma N,Harrison ^[4] ; Kevin Manuel,Méndez-Acevedo ^[5] ; Jacalyn S,MacGowan ^[6] ; Harrison H,Wells ^[4] ; Max S,Hiltabidle ^[4] ; Azhwar,Raghunath ^[7] ; Jordan A,Shavit ^[8] ; Daniela,Panáková ^[9] ; Margot L K,Williams ^[6] ; Mark D,Robinson ^[3] ; Christian,Mosimann ^[4] ; Alexa,Burger ^[10]

作者单位： Department of Pediatrics, Section of Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Department of Molecular Life Sciences, University of Zürich, Zürich, Switzerland. ^[1] Department of Molecular Life Sciences, University of Zürich, Zürich, Switzerland. ^[2] Department of Molecular Life Sciences, University of Zürich, Zürich, Switzerland; SIB Swiss Institute of Bioinformatics, University of Zürich, Zürich, Switzerland. ^[3] Department of Pediatrics, Section of Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. ^[4] Max Delbrück Center (MDC) for Molecular Medicine in the Helmholtz Association, Berlin-Buch, Germany. ^[5] Center for Precision Environmental Health, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. ^[6] Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA. ^[7] Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, USA. ^[8] Max Delbrück Center (MDC) for Molecular Medicine in the Helmholtz Association, Berlin-Buch, Germany; University Hospital Schleswig Holstein, Kiel, Germany; German Centre for Cardiovascular Research (DZHK), Partner Site Hamburg, Kiel, Lübeck, Germany. ^[9] Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address: alexa.burger@cuanschutz.edu. ^[10]

关键词 Development Hematopoiesis Morphogenesis Non-canonical wnt Thrombocytopenia Zebrafish