Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephalitis in seven new cohorts.
第一作者:
Adrian,Gervais
第一单位:
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) U1163, Necker Hospital for Sick Children, Paris, France, EU.;Paris Cité University, Imagine Institute, Paris, France, EU.
作者:
Adrian,Gervais [1]
;
Francesca,Trespidi [2]
;
Alessandro,Ferrari [3]
;
Francesca,Rovida [4]
;
Astrid,Marchal [1]
;
Stefania,Croce [5]
;
Irene,Cassaniti [4]
;
Mattia,Moratti [6]
;
Jennifer L,Uhrlaub [7]
;
David M,Florian [8]
;
Karin,Stiasny [8]
;
Elisa,Burdino [9]
;
Micol,Angelini [10]
;
Lucy,Bizien [1]
;
Daniele,Lilleri [11]
;
Veronica,Codullo [12]
;
Tal,Freund [13]
;
Yael,Paran [14]
;
Avi,Gadoth [15]
;
Roni,Biran [14]
;
Alessandro,Mancon [16]
;
Camilla,Lucca [17]
;
Stefania,Vogiatzis [17]
;
Monia,Pacenti [18]
;
Mélodie,Aubart [19]
;
Marco,Zecca [20]
;
Patrizia,Comoli [5]
;
Maria Antonietta,Avanzini [21]
;
Jacques,Fellay [22]
;
Antonio,Piralla [11]
;
Francesca,Conti [6]
;
Alberto,Dolci [23]
;
Luisa,Barzon [24]
;
Valeria,Ghisetti [9]
;
Tiziana,Lazzarotto [25]
;
Danilo,Cereda [26]
;
Alessandro,Aiuti [27]
;
Emmanuelle,Jouanguy [28]
;
Paul,Bastard [29]
;
Margaret R,MacDonald [30]
;
Charles M,Rice [30]
;
Anne,Puel [28]
;
Laurent,Abel [28]
;
Giada,Rossini [31]
;
Davide,Mileto [16]
;
Yannick,Simonin [32]
;
Anna,Nagy [33]
;
David,Hagin [13]
;
Kristy O,Murray [34]
;
Fausto,Baldanti [4]
;
Judith H,Aberle [8]
;
Aurélie,Cobat [28]
;
Shen-Ying,Zhang [28]
;
Jean-Laurent,Casanova [35]
;
Alessandro,Borghesi [36]
作者单位:
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) U1163, Necker Hospital for Sick Children, Paris, France, EU.;Paris Cité University, Imagine Institute, Paris, France, EU.
[1]
Host-Pathogen Group and Neonatal Intensive Care Unit, San Matteo Research Hospital, Pavia, Italy, EU.;School of Life Sciences, Swiss Federal Institute of Technology, Lausanne, Switzerland.;Medical Genetics, Department of Molecular Medicine, University of Pavia, Pavia, Italy, EU.
[2]
Microbiology and Virology Unit, San Matteo Research Hospital, Pavia, Italy, EU.;Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy, EU.
[3]
Microbiology and Virology Unit, San Matteo Research Hospital, Pavia, Italy, EU.;Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy, EU.
[4]
Cell Factory, San Matteo Research Hospital, Pavia, Italy, EU.
[5]
Pediatric Unit, University Hospital of Bologna, Bologna, Italy, EU.;Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy, EU.
[6]
Department of Immunobiology, The University of Arizona, Tucson, Arizona, USA.
[7]
Center for Virology, Medical University of Vienna, Vienna, Austria, EU.
[8]
Laboratory of Microbiology and Virology, Amedeo di Savoia Hospital, Turin, Italy, EU.
[9]
Host-Pathogen Group and Neonatal Intensive Care Unit, San Matteo Research Hospital, Pavia, Italy, EU.
[10]
Microbiology and Virology Unit, San Matteo Research Hospital, Pavia, Italy, EU.
[11]
Rheumatology Unit, San Matteo Research Hospital, Pavia, Italy, EU.
[12]
Allergy and Clinical Immunology Unit, Department of Medicine, Tel Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel.
[13]
Infection diseases department, Tel-Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel.
[14]
Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
[15]
Laboratory of Clinical Microbiology, Virology and Bioemergencies, Luigi Sacco Hospital, Milan, Italy, EU.
[16]
Department of Molecular Medicine, University of Padua, Padua, Italy, EU.
[17]
Microbiology and Virology Unit, Padua University Hospital, Padua, Italy, EU.
[18]
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) U1163, Necker Hospital for Sick Children, Paris, France, EU.;Paris Cité University, Imagine Institute, Paris, France, EU.;Pediatric Neurology Department, Necker Hospital for Sick Children, Paris, France, EU.
[19]
Pediatric Hematology-Oncology Unit, San Matteo Research Hospital, Pavia, Italy, EU.
[20]
Cell Factory, San Matteo Research Hospital, Pavia, Italy, EU.;Pediatric Hematology-Oncology Unit, San Matteo Research Hospital, Pavia, Italy, EU.
[21]
School of Life Sciences, Swiss Federal Institute of Technology, Lausanne, Switzerland.;Precision Medicine Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
[22]
Laboratory of Clinical Microbiology, Virology and Bioemergencies, Luigi Sacco Hospital, Milan, Italy, EU.;Department of Biomedical and Clinical Sciences (DIBIC), University of Milan, Milan, Italy, EU.
[23]
Department of Molecular Medicine, University of Padua, Padua, Italy, EU.;Microbiology and Virology Unit, Padua University Hospital, Padua, Italy, EU.
[24]
Microbiology Unit, University Hospital of Bologna, Bologna, Italy, EU.;Section of Microbiology, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy, EU.
[25]
DG Welfare, Lombardy, Italy, EU.
[26]
Pediatric Immunohematology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy, EU.;San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, Milan, Italy, EU.;Vita-Salute San Raffaele University, Milan, Italy, EU.
[27]
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) U1163, Necker Hospital for Sick Children, Paris, France, EU.;Paris Cité University, Imagine Institute, Paris, France, EU.;St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
[28]
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) U1163, Necker Hospital for Sick Children, Paris, France, EU.;Paris Cité University, Imagine Institute, Paris, France, EU.;St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.;Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, Paris, France, EU.
[29]
Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
[30]
Microbiology Unit, University Hospital of Bologna, Bologna, Italy, EU.
[31]
Pathogenesis and Control of Chronic and Emerging Infections, University of Montpellier, INSERM, EFS, Montpellier, France, EU.
[32]
National Reference Laboratory for Viral Zoonoses, National Public Health Center, Budapest, Hungary, EU.
[33]
Department of Pediatrics, Section of Pediatric Tropical Medicine, Center for Human Immunobiology, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA.
[34]
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) U1163, Necker Hospital for Sick Children, Paris, France, EU.;Paris Cité University, Imagine Institute, Paris, France, EU.;St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.;Howard Hughes Medical Institute, New York, NY, USA.;Department of Pediatrics, Necker Hospital for Sick Children, Paris, France, EU.
[35]
Host-Pathogen Group and Neonatal Intensive Care Unit, San Matteo Research Hospital, Pavia, Italy, EU.;School of Life Sciences, Swiss Federal Institute of Technology, Lausanne, Switzerland.;Neonatal Intensive Care Unit, Mother, Child and Adolescent Department, Geneva University Hospitals, Geneva, Switzerland.;Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland.
[36]
DOI
10.1101/2025.08.31.25334556
PMID
40950468
发布时间
2026-03-24
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medRxiv
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