首页> Genome research> Recalibrating differential gene expression by genetic dosage variance prioritizes functionally relevant genes.

Recalibrating differential gene expression by genetic dosage variance prioritizes functionally relevant genes.

导出 OA

翻译打印收藏纠错

第一作者： Philipp,Rentzsch

第一单位： Science for Life Laboratory, Department of Gene Technology, KTH Royal Institute of Technology, 17165 Solna, Sweden; philipp.rentzsch@scilifelab.se tuuli.lappalainen@scilifelab.se.

作者： Philipp,Rentzsch ^[1] ; Aaron,Kollotzek ^[2] ; Kaushik Ram,Ganapathy ^[3] ; Pejman,Mohammadi ^[4] ; Tuuli,Lappalainen ^[5]

作者单位： Science for Life Laboratory, Department of Gene Technology, KTH Royal Institute of Technology, 17165 Solna, Sweden; philipp.rentzsch@scilifelab.se tuuli.lappalainen@scilifelab.se. ^[1] Science for Life Laboratory, Department of Gene Technology, KTH Royal Institute of Technology, 17165 Solna, Sweden. ^[2] Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, California 92037, USA. ^[3] Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Washington 98101, USA.;Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington 98105, USA.;Department of Genome Science, University of Washington, Seattle, Washington 98195, USA. ^[4] Science for Life Laboratory, Department of Gene Technology, KTH Royal Institute of Technology, 17165 Solna, Sweden; philipp.rentzsch@scilifelab.se tuuli.lappalainen@scilifelab.se.;New York Genome Center, New York, New York 10013, USA.;Department of Systems Biology, Columbia University, New York, New York 10032, USA. ^[5]

医学主题词人类(Humans);基因剂量(Gene Dosage);基因表达谱(Gene Expression Profiling);基因表达调控(Gene Expression Regulation);序列分析, RNA(Sequence Analysis, RNA)

DOI 10.1101/gr.280360.124

PMID 40962677

发布时间 2026-05-07

基金项目

R01 GM140287/GM/NIGMS NIH HHS/United States

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交