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Comparative Analysis of Deep Mutational Scanning Datasets in Enteroviruses A and B Identifies Functional Divergence and Therapeutic Targets.

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第一作者： Beatriz,Álvarez-Rodríguez

第一单位： Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain.

作者： Beatriz,Álvarez-Rodríguez ^[1] ; William,Bakhache ^[2] ; Lauren,McCormick ^[3] ; Ron,Geller ^[1] ; Patrick T,Dolan ^[2]

作者单位： Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain. ^[1] Quantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, USA. ^[2] Quantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, USA.;Department of Biology, University of Oxford, Oxford, UK. ^[3]

关键词 coxsackievirus B3 deep mutational scanning drug discovery enterovirus A71 enteroviruses

DOI 10.21203/rs.3.rs-7483105/v1

PMID 40964030

发布时间 2026-03-10

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Comparative Analysis of Deep Mutational Scanning Datasets in Enteroviruses A and B Identifies Functional Divergence and Therapeutic Targets.

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Comparative Analysis of Deep Mutational Scanning Datasets in Enteroviruses A and B Identifies Functional Divergence and Therapeutic Targets.

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