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Nuclear-cytoplasmic translocation of MCIDAS couples transcription with massive de novo centriole biogenesis in multiciliated cells.

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第一作者: Hao,Lu
第一单位: Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A(∗)STAR), Proteos, 61 Biopolis Drive, Singapore 138673, Singapore.
作者单位: Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A(∗)STAR), Proteos, 61 Biopolis Drive, Singapore 138673, Singapore. [1] Skin Research Institute of Singapore, 11 Mandalay Road #17-01 Clinical Sciences Building, Singapore 308232, Singapore. [2] Lee Kong Chian School of Medicine, Nanyang Technological University, Clinical Sciences Building, 11 Mandalay Road, Singapore 308232, Singapore. [3] Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A(∗)STAR), Proteos, 61 Biopolis Drive, Singapore 138673, Singapore; Division of Clinical Medicine, School of Medicine and Public Health, University of Sheffield, Sheffield S10 2JF, UK. [4] Biotechnology Research and Innovation Council - National Institute of Biomedical Genomics (BRIC-NIBMG), Kalyani, India; Biotechnology Research and Innovation Council - Regional Centre for Biotechnology (BRIC-RCB), Faridabad, India. [5] Institut de Biologie de l'École Normale Supérieure (IBENS), CNRS, UMR 8197, INSERM, U1024, Paris Sciences et Lettres (PSL), Research University, Paris, France. [6] Infectious Disease Labs (IDLabs), Agency for Science, Technology and Research (A(∗)STAR), 8a Biomedical Grove, #05-13, Immunos, Singapore 1386348, Singapore; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A(∗)STAR), 30 Biopolis Street, #07-01, Matrix, Singapore 138671, Singapore. [7] Division of Clinical Medicine, School of Medicine and Public Health, University of Sheffield, Sheffield S10 2JF, UK. [8] Bioinformatics Institute (BII), Agency for Science, Technology and Research (A(∗)STAR), 30 Biopolis Street, #07-01, Matrix, Singapore 138671, Singapore; Yong Loo Lin School of Medicine and Department of Biological Sciences, National University of Singapore, Singapore 117597, Singapore. [9] Biotechnology Research and Innovation Council - National Institute of Biomedical Genomics (BRIC-NIBMG), Kalyani, India. [10] Skin Research Institute of Singapore, 11 Mandalay Road #17-01 Clinical Sciences Building, Singapore 308232, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Clinical Sciences Building, 11 Mandalay Road, Singapore 308232, Singapore. [11] Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A(∗)STAR), Proteos, 61 Biopolis Drive, Singapore 138673, Singapore; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119288, Singapore. Electronic address: sudipto_roy@a-star.edu.sg. [12]
DOI 10.1016/j.celrep.2025.116321
PMID 40974574
发布时间 2025-11-01
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