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Targeting ROS-metabolism dual pathways to trigger PANoptosis by cobalt-vanadium oxides biomimetic nanocakes for tumor immunotherapy.

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第一作者： Silin,Du

第一单位： Department of Thyroid and Breast Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, China; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China.

作者： Silin,Du ^[1] ; Guangyu,Ma ^[2] ; Xiang,Li ^[3] ; Minghao,Chao ^[4] ; Liying,Fan ^[1] ; Zhiqiang,Zhao ^[2] ; Rongze,Tang ^[2] ; Junjie,Li ^[2] ; Chaonan,Jing ^[2] ; Yufan,Liu ^[2] ; Dehong,Yu ^[5] ; Zhao,Liu ^[6] ; Fenglei,Gao ^[7]

作者单位： Department of Thyroid and Breast Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, China; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China. ^[1] Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China. ^[2] Department of Orthopedics, The Affiliated Huai'an Hospital of Xuzhou Medical University, The Second People's Hospital of Huai'an, Huai'an, 223002, China. ^[3] Department of Orthopaedic Surgery, Lishui Central Hospital and Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, Zhejiang Province, China. ^[4] Department of Oncology, The Affiliated Pizhou Hospital of Xuzhou Medical University, Pizhou, Jiangsu, 221399, China. Electronic address: 15380117222@163.com. ^[5] Department of Thyroid and Breast Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, China; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China. Electronic address: xylzhao9999@163.com. ^[6] Department of Thyroid and Breast Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, China; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China; Department of Oncology, The Affiliated Pizhou Hospital of Xuzhou Medical University, Pizhou, Jiangsu, 221399, China. Electronic address: flgao@xzhmu.edu.cn. ^[7]

关键词 Cobalt Glutamine metabolism Immunotherapy PANoptosis Vanadium