首页> Journal for immunotherapy of cancer> Tertiary lymphoid structures in Merkel cell carcinoma facilitate naïve and central memory T-cell infiltration linked to immunotherapy response.

Tertiary lymphoid structures in Merkel cell carcinoma facilitate naïve and central memory T-cell infiltration linked to immunotherapy response.

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第一作者： Nalini,Srinivas

第一单位： Dermatology, University of Duisburg-Essen, Essen, Germany.;Translational Skin Cancer Research, Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKFZ, Heidelberg, Germany.

作者： Nalini,Srinivas ^[1] ; Ivelina,Spassova ^[1] ; Kuan Cheok,Lei ^[1] ; Jiwei,Gao ^[2] ; María José,Pino ^[3] ; Giovanni,Giglio ^[4] ; Simo,Kitanovski ^[5] ; Mazdak,Dalkoohi ^[1] ; Elisabeth,Livingstone ^[6] ; Ulrike,Leiter ^[7] ; Peter,Mohr ^[8] ; Thilo,Gambichler ^[9] ; Ingo,Stoffels ^[10] ; Selma,Ugurel ^[11] ; Phyllis Fung-Yi,Cheung ^[12] ; Camilla,Engblom ^[3] ; Weng-Onn,Lui ^[2] ; Jürgen Christian,Becker ^[13]

作者单位： Dermatology, University of Duisburg-Essen, Essen, Germany.;Translational Skin Cancer Research, Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKFZ, Heidelberg, Germany. ^[1] Oncology-Pathology, Karolinska Institutet, Solna, Sweden. ^[2] Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden. ^[3] Oncology-Pathology, Karolinska Institutet, Solna, Sweden.;Bridge Institute of Experimental Tumor Therapy (BIT), University of Duisburg-Essen, Essen, Germany. ^[4] Bioinformatics & Computational Biophysics, University of Duisburg-Essen, Essen, Germany. ^[5] Dermatology, University of Duisburg-Essen, Essen, Germany. ^[6] Division for Dermatooncology, Department of Dermatology, Universitätsklinikum Tübingen, Tubingen, Germany. ^[7] Elbe Kliniken Buxtehude, Buxtehude, Germany. ^[8] Department of Dermatology, Ruhr University Bochum, Bochum, Germany. ^[9] Dermatology, Kliniken Essen-Mitte Evangelische Huyssens-Stiftung/Knappschaft GmbH, Essen, Germany. ^[10] Dermatology, University of Duisburg-Essen, Essen, Germany.;Dermatology, Bielefeld University, Medical School and University Medical Center OWL, Bielefeld, UK. ^[11] Bridge Institute of Experimental Tumor Therapy (BIT), University of Duisburg-Essen, Essen, Germany.;Division of Solid Tumor Translational Oncology, Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKFZ, Heidelberg, Germany. ^[12] Dermatology, University of Duisburg-Essen, Essen, Germany j.becker@dkfz.de.;Translational Skin Cancer Research, Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKFZ, Heidelberg, Germany. ^[13]

关键词 T cell receptor - TCR Tumor microenvironment - TME biomarker immune checkpoint inhibitor skin cancer