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Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.

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第一作者: Tao,Zhang
第一单位: Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, China.;Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, China.;NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, China.
作者: Tao,Zhang [1] ; Hongzhi,Lv [1] ; Siming,Jia [1] ; Lijun,Wang [2] ; Weijian,Liu [3] ; Kai,Ding [1] ; Xiaofeng,Du [1] ; Guangzhao,Hou [1] ; Zhiyong,Hou [4] ; Yingze,Zhang [4] ; Weiguo,Zou [5] ; Wei,Chen [6] ; Yanbin,Zhu [7]
作者单位: Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, China.;Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, China.;NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, China. [1] Hainan Institute of Regenerative Orthopedics and Sports Medicine, Hainan Academy of Medical Sciences and School of Basic Medicine, Hainan Medical University, Haikou, Hainan, China. wanglijun2014@sibcb.ac.cn.;Key Laboratory of RNA Innovation, Science and Engineering, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences Chinese Academy of Sciences, Shanghai, China. wanglijun2014@sibcb.ac.cn. [2] Department of Orthopaedics Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, China. [3] Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, China.;Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, China.;NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, China.;Engineering Research Center of Orthopedic MinimallyInvasive Intelligent Equipment, Ministry of Education, Shijiazhuang, Hebei, China. [4] Hainan Institute of Regenerative Orthopedics and Sports Medicine, Hainan Academy of Medical Sciences and School of Basic Medicine, Hainan Medical University, Haikou, Hainan, China.;Key Laboratory of RNA Innovation, Science and Engineering, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences Chinese Academy of Sciences, Shanghai, China. [5] Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, China. surgeonchenwei@126.com.;Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, China. surgeonchenwei@126.com.;NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, China. surgeonchenwei@126.com.;Engineering Research Center of Orthopedic MinimallyInvasive Intelligent Equipment, Ministry of Education, Shijiazhuang, Hebei, China. surgeonchenwei@126.com. [6] Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, China. 38600312@hebmu.edu.cn.;Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, China. 38600312@hebmu.edu.cn.;NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, China. 38600312@hebmu.edu.cn.;Engineering Research Center of Orthopedic MinimallyInvasive Intelligent Equipment, Ministry of Education, Shijiazhuang, Hebei, China. 38600312@hebmu.edu.cn. [7]
DOI 10.1038/s41413-025-00459-4
PMID 40993116
发布时间 2025-09-27
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2025年13卷1期

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