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Efficient fermentative production of SAM through multidimensional engineering of Saccharomyces cerevisiae.

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第一作者： Yuanshan,Wang

第一单位： Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, No. 18, Chaowang Road, Hangzhou, 310014, Zhejiang Province, P. R. China.;Engineering Research Centre of Bioconversion and Biopurification, Ministry of Education, Zhejiang University of Technology, No. 18, Chaowang Road, Hangzhou, 310014, Zhejiang Province, P. R. China.;The National and Local Joint Engineering Research Centre for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, 310014, P. R. China.

作者： Yuanshan,Wang ^[1] ; Liangzhuang,Tan ^[1] ; Meijing,Li ^[1] ; Lang,Wang ^[1] ; Zuoyu,Huang ^[1] ; Puhong,Yi ^[1] ; Chunyue,Weng ^[1] ; Zhongce,Hu ^[1] ; Zhiqiang,Liu ^[2] ; Yuguo,Zheng ^[1]

作者单位： Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, No. 18, Chaowang Road, Hangzhou, 310014, Zhejiang Province, P. R. China.;Engineering Research Centre of Bioconversion and Biopurification, Ministry of Education, Zhejiang University of Technology, No. 18, Chaowang Road, Hangzhou, 310014, Zhejiang Province, P. R. China.;The National and Local Joint Engineering Research Centre for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. ^[1] Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, No. 18, Chaowang Road, Hangzhou, 310014, Zhejiang Province, P. R. China. microliu@zjut.edu.cn.;Engineering Research Centre of Bioconversion and Biopurification, Ministry of Education, Zhejiang University of Technology, No. 18, Chaowang Road, Hangzhou, 310014, Zhejiang Province, P. R. China. microliu@zjut.edu.cn.;The National and Local Joint Engineering Research Centre for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, 310014, P. R. China. microliu@zjut.edu.cn. ^[2]

关键词 S-adenosyl-L-methionine Genome shuffling Metabolic engineering Transcriptome analysis UV-ARTP compound mutagenesis