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AZP2006 in Progressive Supranuclear Palsy: Outcomes from a Phase 2a Multicenter, Randomized Trial, and Open-Label Extension on Safety, Biomarkers, and Disease Progression.

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第一作者： Jean-Christophe,Corvol

第一单位： Sorbonne Université, Assistance Publique Hôpitaux de Paris, Paris Brain Institute, ICM, Inserm, CNRS, Department of Neurology, CIC Neurosciences, Hôpital Pitié-Salpêtrière, Paris, France.

作者： Jean-Christophe,Corvol ^[1] ; Mickael Alexandre,Obadia ^[2] ; Caroline,Moreau ^[3] ; Louise-Laure,Mariani ^[1] ; Jean-Philippe,Brandel ^[2] ; David,Devos ^[3] ; Sara,Sambin ^[1] ; Nicolas,Carrière ^[3] ; Günter,Höglinger ^[4] ; Marie,Lebouteux ^[2] ; Graziella,Mangone ^[1] ; Noelle,Callizot ^[5] ; Aurélien,Blondel ^[5] ; Olivier,Defert ^[5] ; Cecilia,Estrella ^[5] ; Artin,Karapet ^[5] ; Philippe,Verwaerde ^[5] ; Luc,Defebvre ^[3]

作者单位： Sorbonne Université, Assistance Publique Hôpitaux de Paris, Paris Brain Institute, ICM, Inserm, CNRS, Department of Neurology, CIC Neurosciences, Hôpital Pitié-Salpêtrière, Paris, France. ^[1] Hospital Foundation Adolphe de Rothschild, Neurology Federation, Parkinson Unit, Paris, France. ^[2] Lille University. Inserm 1172, Department of Neurology, CHU Lille, Lille, France. ^[3] Department of Neurology, LMU University Hospital, Ludwig-Maximilians-Universität (LMU), German Center for Neurodegenerative Diseases (DZNE), Cluster for Systems Neurology (SyNergy), Munich, Germany. ^[4] Alzprotect, Loos, France. ^[5]

关键词 lysosome progranulin progressive supranuclear palsy tauopathy