Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer's Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial.
第一作者:
Susan,Abushakra
第一单位:
Alzheon, Inc, 111 Speen Street, Suite 306, Framingham, MA, 01701, USA. susan.abushakra@alzheon.com.
作者:
医学主题词
人类(Humans);双盲法(Double-Blind Method);女(雌)性(Female);阿尔茨海默病(Alzheimer Disease);老年人(Aged);男(雄)性(Male);载脂蛋白E4(Apolipoprotein E4);老年人, 80以上(Aged, 80 and over);中年人(Middle Aged);磁共振成像(Magnetic Resonance Imaging);投药, 口服(Administration, Oral);纯合子(Homozygote);治疗结果(Treatment Outcome);脑(Brain)
DOI
10.1007/s40265-025-02250-5
PMID
41015981
发布时间
2025-12-08
- 浏览0
Drugs
1455-1472页
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