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Distant metastases of melanoma exhibit varying extent of intrapatient proteogenomic heterogeneity.

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第一作者: Beata,Szeitz
第一单位: Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary.
作者单位: Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary. [1] Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.;European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands. [2] Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.;Genome Integrity and DNA Repair Core Group, Hungarian Centre of Excellence for Molecular Medicine (HCEMM), University of Szeged, Szeged, Hungary. [3] Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.;Competence Centre of the Life Sciences Cluster of the Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Szeged, Hungary. [4] Division of Clinical Protein Science & Imaging, Department of Biomedical Engineering, Lund University, Lund, Sweden.;Department of Translational Medicine, Skåne University Hospital Malmö, Lund University, Malmö, Sweden. [5] Department of Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden. [6] Department of Dermatology, Venerology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary. [7] Division of Clinical Protein Science & Imaging, Department of Biomedical Engineering, Lund University, Lund, Sweden. [8] Division of Clinical Protein Science & Imaging, Department of Biomedical Engineering, Lund University, Lund, Sweden.;European Cancer Moonshot Lund Center, Lund, Sweden. [9] Section of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden. [10] Department of Translational Medicine, Skåne University Hospital Malmö, Lund University, Malmö, Sweden. [11] Division of Clinical Protein Science & Imaging, Department of Biomedical Engineering, Lund University, Lund, Sweden.;BioMS-Swedish National Infrastructure for Biological Mass Spectrometry, Lund University, Lund, Sweden. [12] Department of Translational Medicine, Skåne University Hospital Malmö, Lund University, Malmö, Sweden.;European Cancer Moonshot Lund Center, Lund, Sweden. [13] Department of Dermatology, Venerology and Dermatooncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.;HCEMM-SU Translational Dermatology Research Group, Semmelweis University, Budapest, Hungary.;Department of Physiology, Semmelweis University, Budapest, Hungary. [14] Division of Clinical Protein Science & Imaging, Department of Biomedical Engineering, Lund University, Lund, Sweden.;European Cancer Moonshot Lund Center, Lund, Sweden.;Chemistry Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. [15] Department of Biochemistry and Molecular Biology, University of Szeged, Szeged, Hungary.;Hungarian Research Network Biological Research Center, Institute of Biochemistry, Szeged, Hungary. [16] Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary. [17] European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands. [18] Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.;Genome Integrity and DNA Repair Core Group, Hungarian Centre of Excellence for Molecular Medicine (HCEMM), University of Szeged, Szeged, Hungary.;Competence Centre of the Life Sciences Cluster of the Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Szeged, Hungary. [19] Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.;Howard Hughes Medical Institute, Dallas, Texas, USA. [20] Institute for Systems Genetics, NYU Grossman School of Medicine, New York, New York, USA.;Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, New York, USA. [21] Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands. [22] Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary. [23]
DOI 10.1002/ctm2.70477
PMID 41017066
发布时间 2025-10-02
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Clinical and translational medicine

Clinical and translational medicine

2025年15卷10期

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