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Ru(II) Complex-Mediated Phase Separation Amplifies Photocatalytic RNA Damage to Stimulate RIG‑I Immunotherapy.

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第一作者： Xiao-Xiao,Chen

第一单位： MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, Sun Yat-Sen University, Guangzhou 510006, P. R. China.

作者： Xiao-Xiao,Chen ^[1] ; Xia,Mu ^[2] ; Zhi-Yuan,Li ^[1] ; Kun,Peng ^[1] ; Qing-Hua,Shen ^[1] ; Yue-Bin,Zhang ^[3] ; Cai-Ping,Tan ^[4]

作者单位： MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, Sun Yat-Sen University, Guangzhou 510006, P. R. China. ^[1] State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, P. R. China. ^[2] Interdisciplinary Research Center for Biology and Chemistry, Liaoning Normal University, Dalian, Liaoning 116029, China. ^[3] MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, Sun Yat-Sen University, Guangzhou 510006, P. R. China.;Guangdong Basic Research Center of Excellence for Functional Molecular Engineering, Guangzhou 510006, P. R. China.;State Key Laboratory of Anti-Infective Drug Discovery and Development; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China. ^[4]

关键词 antitumor phase separation photodynamic therapy ruthenium complex tumor immune microenvironments

DOI 10.1021/jacsau.5c00867

PMID 41036131

发布时间 2025-10-04

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2025年5卷9期

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Ru(II) Complex-Mediated Phase Separation Amplifies Photocatalytic RNA Damage to Stimulate RIG‑I Immunotherapy.

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Ru(II) Complex-Mediated Phase Separation Amplifies Photocatalytic RNA Damage to Stimulate RIG‑I Immunotherapy.

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