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Microbiome-transcriptome-histology triad enhances survival risk stratification in multiple cancers.

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第一作者： Binsheng,He

第一单位： First Clinical College, Changsha Medical University, Changsha 410219, PR China; Hunan Provincial Key Laboratory of the Traditional Chinese Medicine Agricultural Biogenomics, Changsha Medical University, Changsha 410219, PR China.

作者： Binsheng,He ^[1] ; Yanyu,Ma ^[2] ; Kun,Wang ^[3] ; Pingping,Bing ^[1] ; Lei,Ji ^[4] ; Geng,Tian ^[4] ; Haiyan,Liu ^[5] ; Pingan,He ^[6] ; Jialiang,Yang ^[7]

作者单位： First Clinical College, Changsha Medical University, Changsha 410219, PR China; Hunan Provincial Key Laboratory of the Traditional Chinese Medicine Agricultural Biogenomics, Changsha Medical University, Changsha 410219, PR China. ^[1] Department of Mathematics, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, PR China. ^[2] Geneis Beijing Co., Ltd., Beijing 100102, PR China; School of Mathematical Sciences, Ocean University of China, Qingdao 266100, PR China. ^[3] Geneis Beijing Co., Ltd., Beijing 100102, PR China. ^[4] First Clinical College, Changsha Medical University, Changsha 410219, PR China; Hunan Provincial Key Laboratory of the Traditional Chinese Medicine Agricultural Biogenomics, Changsha Medical University, Changsha 410219, PR China. Electronic address: liuhy_csmu@163.com. ^[5] Department of Mathematics, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, PR China. Electronic address: pinganhe@zstu.edu.cn. ^[6] Geneis Beijing Co., Ltd., Beijing 100102, PR China. Electronic address: yangjl@geneis.cn. ^[7]

关键词 Cancer prognosis Microbiome Multimodal fusion Pathological image Transcriptome

医学主题词人类(Humans);肿瘤(Neoplasms);预后(Prognosis);危险性评估(Risk Assessment);女(雌)性(Female)

DOI 10.1016/j.compbiolchem.2025.108703

PMID 41043335

发布时间 2025-12-14

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