首页> Translational psychiatry> LRRK2 deficiency mitigates amyloid β deposition-mediated pathology in a murine Alzheimer's disease model by reprogramming microglia.

LRRK2 deficiency mitigates amyloid β deposition-mediated pathology in a murine Alzheimer's disease model by reprogramming microglia.

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第一作者： Qiuyang,Zhang

第一单位： Department of Neurology, Fuzhou Second General Hospital, 47 Shangteng Road, Fuzhou, 350007, China.;Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou, 350001, China.

作者： Qiuyang,Zhang ^[1] ; Hsuan,Lo ^[2] ; Yue,Song ^[3] ; Linjuan,Feng ^[4] ; Hanlin,You ^[4] ; Xiaochun,Chen ^[4] ; Yanping,Wang ^[5] ; Xiaodong,Pan ^[6]

作者单位： Department of Neurology, Fuzhou Second General Hospital, 47 Shangteng Road, Fuzhou, 350007, China.;Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou, 350001, China. ^[1] Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.;Medical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China. ^[2] Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou, 350001, China.;Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China. ^[3] Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou, 350001, China.;Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China.;Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China.;Institute of Clinical Neurology, Fujian Medical University, 29 Xinquan Road, Fuzhou, 350001, China. ^[4] Department of Endocrinology, Fujian Medical University Union Hospital, Fuzhou, 350001, China. ^[5] Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou, 350001, China. pxd77316@163.com.;Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China. pxd77316@163.com.;Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China. pxd77316@163.com.;Institute of Clinical Neurology, Fujian Medical University, 29 Xinquan Road, Fuzhou, 350001, China. pxd77316@163.com.;Clinical Research Center for Precision Diagnosis and Treatment of Neurological Diseases of Fujian Province, Fuzhou, China. pxd77316@163.com. ^[6]