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An in vivo PET/CT investigation of mitochondrial complex 1, sigma 1, and synaptic vesicle 2 A in patients with amyotrophic lateral sclerosis.

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第一作者： Edoardo R,de Natale

第一单位： Neurodegeneration Imaging Group, University of Exeter Medical School, London, UK.

作者： Edoardo R,de Natale ^[1] ; Joji P,Verghese ^[1] ; Alana,Terry ^[1] ; Heather,Wilson ^[1] ; Pegah,Khosropanah ^[2] ; Holly,Wright ^[1] ; Luca,Passamonti ^[3] ; Karleyton C,Evans ^[3] ; Robert A,Comley ^[4] ; Hideo,Tsukada ^[5] ; Jan,Passchier ^[6] ; Graham,Searle ^[6] ; Ekaterina,Pererva ^[6] ; Alex,Whittington ^[6] ; Roger,Gunn ^[6] ; Eugenii A,Rabiner ^[6] ; Marios,Politis ^[7]

作者单位： Neurodegeneration Imaging Group, University of Exeter Medical School, London, UK. ^[1] Neurodegeneration Imaging Group, University of Exeter Medical School, London, UK; Oxford Brain Diagnostics, Oxford, UK. ^[2] Biogen, Cambridge, MA, USA. ^[3] AbbVie, North Chicago, IL 69964, USA. ^[4] Hamamatsu Photonics, Hamana, Hamamatsu, Shizuoka 4348601, Japan. ^[5] Perceptive Discovery, Hammersmith Hospital, London, UK. ^[6] Neurodegeneration Imaging Group, University of Exeter Medical School, London, UK. Electronic address: m.politis@exeter.ac.uk. ^[7]

关键词 Amyotrophic lateral sclerosis Mitochondrial complex 1 Neurodegeneration Positron emission tomography SV2A Sigma-1 receptors