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Design, synthesis, and antifungal activity of novel amide imidazole CYP51 inhibitors with aromatic fused ring hydrophobic side chains.

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第一作者： Zixuan,Gao

第一单位： Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University 103 Wenhua Road, Shenhe District 110016 Shenyang China medchemzhao@163.com.

作者： Zixuan,Gao ^[1] ; Wenzhan,Hao ^[1] ; Jinming,Liu ^[1] ; Kejian,Li ^[1] ; Yixiang,Sun ^[1] ; Xudong,Wu ^[1] ; Zirui,Luo ^[1] ; Rui,Liu ^[1] ; Haoyu,Zhang ^[1] ; Nian,Liu ^[1] ; Dongmei,Zhao ^[1] ; Maosheng,Cheng ^[1]

作者单位： Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University 103 Wenhua Road, Shenhe District 110016 Shenyang China medchemzhao@163.com. ^[1]

DOI 10.1039/d5md00632e

PMID 41078575

发布时间 2026-04-22

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Design, synthesis, and antifungal activity of novel amide imidazole CYP51 inhibitors with aromatic fused ring hydrophobic side chains.

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Design, synthesis, and antifungal activity of novel amide imidazole CYP51 inhibitors with aromatic fused ring hydrophobic side chains.

RSC medicinal chemistry

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RSC medicinal chemistry

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