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Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross-Platform Validation.

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第一作者： Manyue,Hu

第一单位： Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College London, London, UK.

作者： Manyue,Hu ^[1] ; Oliver,Robinson ^[2] ; Christina M,Lill ^[3] ; Anna,Matton ^[4] ; Raquel,Puerta ^[5] ; Pilar,Sanz ^[5] ; Merce,Boada ^[6] ; Agustín,Ruiz ^[7] ; Lefkos,Middleton ^[1] ; Alzheimer's Disease Neuroimaging Initiative

作者单位： Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College London, London, UK. ^[1] Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College London, London, UK.;MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. ^[2] Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College London, London, UK.;Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany. ^[3] Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College London, London, UK.;Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. ^[4] ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain. ^[5] ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.;CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain. ^[6] ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.;CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, Texas, USA.;Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health Science Center, San Antonio, Texas, USA. ^[7]

关键词 Alzheimer's disease cognitive dysfunction cohort study machine learning proteomics

DOI 10.1002/acn3.70227

PMID 41083424

发布时间 2025-10-13

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Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross-Platform Validation.

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Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross-Platform Validation.

Annals of clinical and translational neurology

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