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Causal Relationships Between Major Depressive Disorder and Coronary Artery Disease Across Diverse Populations: A Bidirectional Mendelian Randomisation Study.

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第一作者： Sarah,Silva

第一单位： Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.;The African Computational Genomics Research Group (TACG), MRC/UVRI and LSHTM, Entebbe, Uganda.

作者： Sarah,Silva ^[1] ; Dorothea,Nitsch ^[2] ; Segun,Fatumo ^[3]

作者单位： Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.;The African Computational Genomics Research Group (TACG), MRC/UVRI and LSHTM, Entebbe, Uganda. ^[1] Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK. ^[2] Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.;The African Computational Genomics Research Group (TACG), MRC/UVRI and LSHTM, Entebbe, Uganda.;Precision Healthcare University Research Institute, Queen Mary University of London, London, UK. ^[3]

关键词 Mendelian randomisation bidirectional two‐sample Mendelian randomisation analysis coronary artery disease coronary heart disease depression major depressive disorder multi‐ancestry

医学主题词人类(Humans);冠状动脉疾病(Coronary Artery Disease);抑郁症, 更年期(Depressive Disorder, Major);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);孟德尔随机化分析(Mendelian Randomization Analysis);多态性, 单核苷酸(Polymorphism, Single Nucleotide)

DOI 10.1111/tmi.70051

PMID 41094686

发布时间 2026-01-09

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