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Neurotoxicity of propylene glycol butyl ether: Multiomic evidence from human brainspheres.

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第一作者： David,Lopez-Rodriguez

第一单位： Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland; Swiss Centre for Applied Human Toxicology (SCAHT), Basel, Switzerland; Institute of Earth Surface Dynamics, University of Lausanne, Canton de Vaud, Switzerland.

作者： David,Lopez-Rodriguez ^[1] ; David,Pamies ^[2] ; Julien,Boccard ^[3] ; Isabel,Meister ^[3] ; Mathieu,Galmiche ^[3] ; Tatjana,Sajic ^[4] ; Estelle,Maret ^[5] ; Noéline,Héritier ^[2] ; Massimo,Frangiamone ^[2] ; Aurélien,Thomas ^[4] ; Nancy B,Hopf ^[6] ; Serge,Rudaz ^[3] ; Marie-Gabrielle,Zurich ^[7]

作者单位： Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland; Swiss Centre for Applied Human Toxicology (SCAHT), Basel, Switzerland; Institute of Earth Surface Dynamics, University of Lausanne, Canton de Vaud, Switzerland. ^[1] Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland; Swiss Centre for Applied Human Toxicology (SCAHT), Basel, Switzerland. ^[2] Swiss Centre for Applied Human Toxicology (SCAHT), Basel, Switzerland; School of Pharmaceutical Sciences, University of Geneva, CMU, Geneva, Switzerland; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU, Geneva, Switzerland. ^[3] Unit of Forensic Toxicology and Chemistry, CURML, Lausanne and Geneva University Hospitals, Geneva, Switzerland; Faculty Unit of Toxicology, CURML, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland. ^[4] Faculty Unit of Toxicology, CURML, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland. ^[5] Unisanté, Center for Primary Care and Public Health and University of Lausanne, Lausanne, Switzerland. ^[6] Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland; Swiss Centre for Applied Human Toxicology (SCAHT), Basel, Switzerland. Electronic address: mzurich@unil.ch. ^[7]

关键词 Lipidomics Metabolomics Microphysiological system New Approach Methodologies (NAMs)Proteomics Solvents Transcriptomics