首页> Journal of pharmaceutical sciences> Synergistic effect of plunger insertion and siliconization methods on particle formation of an antibody formulation.

Synergistic effect of plunger insertion and siliconization methods on particle formation of an antibody formulation.

导出 LinkOut

翻译打印收藏纠错

第一作者： Alexandra,Lucas

第一单位： Center for Pharmaceutical Biotechnology, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Blvd, MS C238-V20, Aurora, CO 80045, United States.

作者： Alexandra,Lucas ^[1] ; Angelina,Bespalova ^[2] ; Vaibhav,Upadhyay ^[1] ; Leighton,Monroe ^[2] ; Myles,Chetcuti ^[2] ; Chiara,Callegari ^[3] ; Deepak Kumar,Tripathi ^[1] ; David L,Bain ^[1] ; Alessandro,Martini ^[3] ; Anthony,Vico ^[4] ; Krishna M G,Mallela ^[5]

作者单位： Center for Pharmaceutical Biotechnology, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Blvd, MS C238-V20, Aurora, CO 80045, United States. ^[1] US Technology Excellence Center, Stevanato Group, Boston, United States. ^[2] EMEA Technology Excellence Center, Stevanato Group, Piombino Dese, Italy. ^[3] US Technology Excellence Center, Stevanato Group, Boston, United States. Electronic address: anthony.vico@stevanatogroup.com. ^[4] Center for Pharmaceutical Biotechnology, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Blvd, MS C238-V20, Aurora, CO 80045, United States. Electronic address: krishna.mallela@cuanschutz.edu. ^[5]

关键词 Aggregation Analytical ultracentrifugation Antibody Light obscuration size exclusion chromatography Microflow imaging Proteins Silicone oil