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On the path to reference genomes for all biodiversity: laboratory protocols and lessons learned from processing over 2,000 species in the Sanger Tree of Life.

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第一作者： Caroline,Howard

第一单位： Tree of Life, Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom.

作者： Caroline,Howard ^[1] ; Amy,Denton ^[1] ; Benjamin W,Jackson ^[1] ; Adam,Bates ^[2] ; Jessie,Jay ^[3] ; Halyna,Yatsenko ^[1] ; Priyanka Sethu,Raman ^[1] ; Abitha,Thomas ^[1] ; Graeme,Oatley ^[1] ; Raquel Vionette,do Amaral ^[1] ; Zeynep Ene,Göktan ^[1] ; Juan Pablo Narváez,Gómez ^[4] ; Isabelle,Clayton Lucey ^[1] ; Elizabeth,Sinclair ^[1] ; Michael A,Quail ^[5] ; Mark,Blaxter ^[1] ; Kerstin,Howe ^[1] ; Mara K N,Lawniczak ^[1]

作者单位： Tree of Life, Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom. ^[1] Tree of Life, Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom.;Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford OX3 7JX, United Kingdom. ^[2] Tree of Life, Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom.;Ancient Genomics Lab, The Francis Crick Institute, London NW1 1AT, United Kingdom. ^[3] Tree of Life, Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom.;Eukaryotic Annotation Team, EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom. ^[4] Scientific Operations, Wellcome Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom. ^[5]

关键词 HMW DNA Hi-C biodiversity extraction long read protocol reference genome sequencing

医学主题词生物多样性(Biodiversity);基因组(Genome);动物(Animals);基因组学(Genomics);序列分析, DNA(Sequence Analysis, DNA)

DOI 10.1093/gigascience/giaf119

PMID 41129326

发布时间 2026-05-10

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