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Multiplicative and additive interaction effects of vascular risk factor burden with APOE genotypes on dementia: Associations and peripheral biological mechanisms based on a large cohort study.

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第一作者： Ze-Lin,Yang

第一单位： Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China; School of Clinical Medicine, Qingdao University, Qingdao, Shandong, China.

作者： Ze-Lin,Yang ^[1] ; Liang-Yu,Huang ^[1] ; Xin-Yu,Luo ^[2] ; Xiao-Hui,Zhang ^[2] ; Chen-Chen,Tan ^[3] ; Lan,Tan ^[3] ; Fu-Rong,Sun ^[4] ; Wei,Xu ^[5]

作者单位： Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China; School of Clinical Medicine, Qingdao University, Qingdao, Shandong, China. ^[1] Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China. ^[2] Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China; Department of Neurology, Qingdao Hospital of Rehabilitation University, Rehabilitation University, Qingdao, China. ^[3] Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China. Electronic address: haorong68@163.com. ^[4] Department of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, China; Department of Neurology, Qingdao Hospital of Rehabilitation University, Rehabilitation University, Qingdao, China. Electronic address: dr_xuwei@qdu.edu.cn. ^[5]

关键词 All-cause dementia Alzheimer's disease Apoe gene Proteomics Vascular risk factors