Transdiagnostic alterations in white matter microstructure associated with suicidal thoughts and behaviours in the ENIGMA Suicidal Thoughts and Behaviours consortium.
第一作者:
Laura S,van Velzen
第一单位:
Orygen, Parkville, VIC, Australia. laurasvanvelzen@gmail.com.;Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia. laurasvanvelzen@gmail.com.
作者:
Laura S,van Velzen [1]
;
Lejla,Colic [2]
;
Zuriel,Ceja [3]
;
Maria R,Dauvermann [4]
;
Luca M,Villa [5]
;
Hannah S,Savage [6]
;
Yara J,Toenders [7]
;
Niousha,Dehestani [8]
;
Alyssa H,Zhu [9]
;
Adrian I,Campos [10]
;
Lauren E,Salminen [9]
;
Martin,Alda [11]
;
Ingrid,Agartz [12]
;
Nina,Alexander [13]
;
Rosa,Ayesa-Arriola [14]
;
Elizabeth D,Ballard [15]
;
Nerisa,Banaj [16]
;
Carlotta,Barkhau [17]
;
Zeynep,Başgöze [18]
;
Jochen,Bauer [19]
;
Francesco,Benedetti [20]
;
Klaus,Berger [21]
;
Bianca,Besteher [22]
;
Katharina,Brosch [23]
;
Manuel,Canal-Rivero [24]
;
Simon,Cervenka [25]
;
Romain,Colle [26]
;
Colm G,Connolly [27]
;
Emmanuelle,Corruble [26]
;
Philippe,Courtet [28]
;
Baptiste,Couvy-Duchesne [29]
;
Benedicto,Crespo-Facorro [30]
;
Kathryn R,Cullen [18]
;
Udo,Dannlowski [17]
;
Jeremy,Deverdun [31]
;
Ana M,Diaz-Zuluaga [32]
;
Lorielle M F,Dietze [11]
;
Jennifer W,Evans [15]
;
Negar,Fani [33]
;
Kira,Flinkenflügel [17]
;
Naomi P,Friedman [34]
;
Ian H,Gotlib [35]
;
Nynke A,Groenewold [36]
;
Dominik,Grotegerd [17]
;
Tomas,Hajek [11]
;
Alexander S,Hatoum [37]
;
Marco,Hermesdorf [21]
;
Ian B,Hickie [38]
;
Yoshiyuki,Hirano [39]
;
Tiffany C,Ho [40]
;
Yuki,Ikemizu [41]
;
Frank,Iorfino [38]
;
Jonathan C,Ipser [36]
;
Yuko,Isobe [39]
;
Andrea P,Jackowski [42]
;
Fabrice,Jollant [43]
;
Tilo,Kircher [13]
;
Melissa,Klug [17]
;
Sheri-Michelle,Koopowitz [36]
;
Anna,Kraus [17]
;
Axel,Krug [44]
;
Emmanuelle,Le Bars [31]
;
Elisabeth J,Leehr [17]
;
Meng,Li [22]
;
Elizabeth T C,Lippard [45]
;
Carlos,Lopez-Jaramillo [46]
;
Ivan I,Maximov [47]
;
Andrew M,McIntosh [48]
;
Katie A,McLaughlin [49]
;
Sean R,McWhinney [11]
;
Susanne,Meinert [50]
;
Elisa,Melloni [20]
;
Philip B,Mitchell [51]
;
Benson,Mwangi [52]
;
Igor,Nenadić [13]
;
Stener,Nerland [53]
;
Emilie,Olie [28]
;
Victor,Ortiz-García de la Foz [14]
;
Pedro M,Pan [54]
;
Fabricio,Pereira [55]
;
Fabrizio,Piras [16]
;
Federica,Piras [16]
;
Sara,Poletti [20]
;
Andrew E,Reineberg [56]
;
Gloria,Roberts [51]
;
Rafael,Romero-García [57]
;
Matthew D,Sacchet [58]
;
Giovanni A,Salum [59]
;
Anca-Larisa,Sandu [60]
;
Carl M,Sellgren [61]
;
Eiji,Shimizu [62]
;
Harry R,Smolker [63]
;
Jair C,Soares [52]
;
J Douglas,Steele [64]
;
Frederike,Stein [13]
;
Dan J,Stein [65]
;
Benjamin,Straube [13]
;
Lea,Teutenberg [13]
;
Florian,Thomas-Odenthal [13]
;
Paula,Usemann [13]
;
Romain,Valabregue [66]
;
Johanna,Valencia-Echeverry [46]
;
Gerd,Wagner [67]
;
Gordon,Waiter [60]
;
Martin,Walter [22]
;
Heather C,Whalley [68]
;
Mon-Ju,Wu [52]
;
Tony T,Yang [69]
;
Carlos A,Zarate [15]
;
Andre,Zugman [70]
;
Giovana B,Zunta-Soares [52]
;
Kees,van Heeringen [71]
;
Sanne J H,van Rooij [33]
;
Nic,van der Wee [72]
;
Steven,van der Werff [72]
;
Paul M,Thompson [9]
;
Hilary P,Blumberg [73]
;
Anne-Laura,van Harmelen [74]
;
Miguel E,Rentería [3]
;
Neda,Jahanshad [9]
;
ENIGMA Suicidal Thoughts and Behaviours Consortium [75]
;
Lianne,Schmaal
作者单位:
Orygen, Parkville, VIC, Australia. laurasvanvelzen@gmail.com.;Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia. laurasvanvelzen@gmail.com.
[1]
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.;Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.;DZPG (German Center for Mental Health), partner site Halle/Jena/Magdeburg, Halle/Jena/Magdeburg, Germany.
[2]
QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.;School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.
[3]
Institute for Mental Health, School of Psychology, University of Birmingham, Birmingham, UK.;Department of Psychiatry, University of Cambridge, Cambridge, UK.
[4]
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
[5]
Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia.;Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia.
[6]
Orygen, Parkville, VIC, Australia.;Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia.;Department of Psychology, Education and Child Studies, Erasmus University Rotterdam, Rotterdam, the Netherlands.
[7]
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia.;School of Psychology, Deakin University, Melbourne, VIC, Australia.
[8]
Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
[9]
QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.;School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.;Regeneron Genetics Center, Tarrytown, NY, USA.
[10]
Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.
[11]
Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.;Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.;Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
[12]
Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.;Center for Mind, Brain, and Behavior (CMBB), University of Marburg, Marburg, Germany.
[13]
Department of Psychiatry. Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria, Santander, Spain.
[14]
Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
[15]
Laboratory of Neuropsychiatry, Clinical Neuroscience and Neurorehabilitation Department, Santa Lucia Foundation IRCCS, Rome, Italy.
[16]
Institute for Translational Psychiatry, University of Münster, Münster, Germany.
[17]
Department of Psychiatry and Behavioral Sciences, University of Minnesota Medical School, Minneapolis, MN, USA.
[18]
Clinic for Radiology, University Hospital Münster, Münster, Germany.
[19]
Division of Neuroscience, Psychiatry and Psychobiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
[20]
Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.
[21]
Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.;DZPG (German Center for Mental Health), partner site Halle/Jena/Magdeburg, Halle/Jena/Magdeburg, Germany.
[22]
Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.;Center for Mind, Brain, and Behavior (CMBB), University of Marburg, Marburg, Germany.;Institute of Behavioral Sciences, Feinstein Institutes for Medical Research, Manhasset, NY, USA.
[23]
Instituto de Biomedicina de Sevilla (IBiS)/HUVR/CSIC/Universidad de Sevilla. CIBERSAM (ISCIII), Seville, Spain.;Mental Health Service, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
[24]
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.;Department of Medical Sciences, Psychiatry, Uppsala University, Uppsala, Sweden.
[25]
MOODS Team, INSERM 1018, CESP, Université Paris-Saclay, Faculté de Médecine Paris-Saclay, Service Hospitalo-Universitaire de Psychiatrie de Bicêtre, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Saclay, Hôpital de Bicêtre, Le Kremlin Bicêtre, F-94275, France.
[26]
Department of Biomedical Sciences, Florida State University, Tallahassee, FL, USA.
[27]
Department of Emergency Psychiatry and Acute Care, Lapeyronie Hospital, CHU Montpellier, Montpellier, France.;IGF, Univ. Montpellier, CNRS, INSERM, Montpellier, France.
[28]
Institute for Molecular Bioscience, the University of Queensland, St Lucia, QLD, Australia.;Sorbonne University, Paris Brain Institute - ICM, CNRS, Inria, Inserm, AP-HP, Hôpital de la Pitié Salpêtrière, F-75013, Paris, France.
[29]
Instituto de Biomedicina de Sevilla (IBiS)/HUVR/CSIC/Universidad de Sevilla. CIBERSAM (ISCIII), Seville, Spain.;Mental Health Service, Hospital Universitario Virgen del Rocío, Sevilla, Spain.;Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III (CIBERSAM), Madrid, Spain.
[30]
Institut d'Imagerie Fonctionnelle Humaine, I2FH, Department of Neuroradiology, Gui de Chauliac Hospital and University of Montpellier, Montpellier, France.;Department of Neuroradiology, Gui de Chauliac Hospital and University of Montpellier, Montpellier, France.
[31]
Center for Neurobehavioral Genetics,Semel Institute for Neuroscience and Behavior David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.;Research Group in Psychiatry GIPSI, Department of Psychiatry, Faculty of Medicine, Universidad de Antioquia, Medellin, Colombia.
[32]
Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.
[33]
Institute for Behavioral Genetics and Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.
[34]
Department of Psychology, Stanford University, Stanford, CA, 94305, USA.
[35]
Department of Psychiatry & Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
[36]
Department of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
[37]
The University of Sydney, Sydney, Australia.
[38]
Research Center for Child Mental Development, Chiba University, Chiba, Japan.;United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University, Chiba University and University of Fukui, Fukui, Japan.
[39]
Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.;Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, USA.
[40]
Research Center for Child Mental Development, Chiba University, Chiba, Japan.;Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba, Japan.
[41]
Østfold University College Department of Education, ICT and Learning, Halden, Norway.;Universidade Federal de São Paulo, São Paulo, Brazil.
[42]
Faculty of Medicine, University Paris-Saclay, Le Kremlin-Bicetre, France.;Clinical Department of Psychiatry and Addictology, Paul Brousse Hospital, APHP, Villejuif, France.;Department of psychiatry, McGill University, Montreal, Canada.
[43]
Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.;Department of Psychiatry, University Hospital Bonn, Bonn, Germany.
[44]
Department of Psychiatry and Behavioral Sciences, Dell Medical School, University of Texas at Austin, Austin, TX, USA.;University of Texas at Austin, Austin, TX, USA.
[45]
Research Group in Psychiatry GIPSI, Department of Psychiatry, Faculty of Medicine, Universidad de Antioquia, Medellin, Colombia.
[46]
Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.;Department of Health and Functioning, Western Norway University of Applied Sciences, Bergen, Norway.
[47]
Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
[48]
Ballmer Institute for Children's Behavioral Health, University of Oregon, Eugene, OR, USA.;Department of Psychology, Harvard University, Cambridge, MA, USA.
[49]
Institute for Translational Psychiatry, University of Münster, Münster, Germany.;Institute for Translational Neuroscience, University of Münster, Münster, Germany.
[50]
Discipline of Psychiatry and Mental Health, School of Clinical Medicine, University of New South Wales, Sydney, Australia.
[51]
Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.;UTHealth Houston School of Behavioral Health Sciences, Houston, TX, USA.
[52]
Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.;Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.
[53]
Universidade Federal de São Paulo, São Paulo, Brazil.
[54]
MIPA, Université de Nîmes, Nimes, France.;Division for clinical research and innovation, University Hospital Center of Nimes, Nimes, France.
[55]
Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.
[56]
Department of Psychiatry, University of Cambridge, Cambridge, UK.;Instituto de Biomedicina de Sevilla (IBiS)/HUVR/CSIC/Universidad de Sevilla. CIBERSAM (ISCIII), Seville, Spain.
[57]
Meditation Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
[58]
Child Mind Institute, New York, NY, USA.;Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre - Porto Alegre, Porto Alegre, Brazil.
[59]
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK.
[60]
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.;Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
[61]
Research Center for Child Mental Development, Chiba University, Chiba, Japan.;United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University, Chiba University and University of Fukui, Fukui, Japan.;Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba, Japan.
[62]
Institute for Cognitive Science, University of Colorado Boulder, Boulder, CO, USA.
[63]
Division of Imaging Science and Technology, Medical School, University of Dundee, Dundee, UK.
[64]
SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry & Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
[65]
Institut du Cerveau et de la Moelle épinière, ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Paris, France.;Centre de Neuro-Imagerie de Recherche, CENIR, ICM, Paris, France.
[66]
Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.;Center for Intervention and Research on adaptive and maladaptive brain Circuits underlying mental health (C-I-R-C), Jena-Magdeburg-Halle, Jena, Germany.
[67]
Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.;Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
[68]
Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.
[69]
National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
[70]
Ghent University, Ghent, Belgium.
[71]
Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.;Leiden Institute for Brain and Cognition. Leiden University Medical Center, Leiden, The Netherlands.
[72]
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.;Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA.;Child Study Center, Yale School of Medicine, New Haven, CT, USA.
[73]
Department of Psychiatry, University of Cambridge, Cambridge, UK.;Education and Child Studies, Leiden University, Leiden, the Netherlands.
[74]
Orygen, Parkville, VIC, Australia.;Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia.
[75]
医学主题词
人类(Humans);自杀意念(Suicidal Ideation);男(雄)性(Male);女(雌)性(Female);弥散张量成像(Diffusion Tensor Imaging);成年人(Adult);自杀未遂(Suicide, Attempted);中年人(Middle Aged);精神障碍(Mental Disorders);各向异性(Anisotropy)
DOI
10.1038/s41398-025-03602-1
PMID
41136374
发布时间
2025-10-28
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Translational psychiatry
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