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Transdiagnostic alterations in white matter microstructure associated with suicidal thoughts and behaviours in the ENIGMA Suicidal Thoughts and Behaviours consortium.

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第一作者: Laura S,van Velzen
第一单位: Orygen, Parkville, VIC, Australia. laurasvanvelzen@gmail.com.;Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia. laurasvanvelzen@gmail.com.
作者: Laura S,van Velzen [1] ; Lejla,Colic [2] ; Zuriel,Ceja [3] ; Maria R,Dauvermann [4] ; Luca M,Villa [5] ; Hannah S,Savage [6] ; Yara J,Toenders [7] ; Niousha,Dehestani [8] ; Alyssa H,Zhu [9] ; Adrian I,Campos [10] ; Lauren E,Salminen [9] ; Martin,Alda [11] ; Ingrid,Agartz [12] ; Nina,Alexander [13] ; Rosa,Ayesa-Arriola [14] ; Elizabeth D,Ballard [15] ; Nerisa,Banaj [16] ; Carlotta,Barkhau [17] ; Zeynep,Başgöze [18] ; Jochen,Bauer [19] ; Francesco,Benedetti [20] ; Klaus,Berger [21] ; Bianca,Besteher [22] ; Katharina,Brosch [23] ; Manuel,Canal-Rivero [24] ; Simon,Cervenka [25] ; Romain,Colle [26] ; Colm G,Connolly [27] ; Emmanuelle,Corruble [26] ; Philippe,Courtet [28] ; Baptiste,Couvy-Duchesne [29] ; Benedicto,Crespo-Facorro [30] ; Kathryn R,Cullen [18] ; Udo,Dannlowski [17] ; Jeremy,Deverdun [31] ; Ana M,Diaz-Zuluaga [32] ; Lorielle M F,Dietze [11] ; Jennifer W,Evans [15] ; Negar,Fani [33] ; Kira,Flinkenflügel [17] ; Naomi P,Friedman [34] ; Ian H,Gotlib [35] ; Nynke A,Groenewold [36] ; Dominik,Grotegerd [17] ; Tomas,Hajek [11] ; Alexander S,Hatoum [37] ; Marco,Hermesdorf [21] ; Ian B,Hickie [38] ; Yoshiyuki,Hirano [39] ; Tiffany C,Ho [40] ; Yuki,Ikemizu [41] ; Frank,Iorfino [38] ; Jonathan C,Ipser [36] ; Yuko,Isobe [39] ; Andrea P,Jackowski [42] ; Fabrice,Jollant [43] ; Tilo,Kircher [13] ; Melissa,Klug [17] ; Sheri-Michelle,Koopowitz [36] ; Anna,Kraus [17] ; Axel,Krug [44] ; Emmanuelle,Le Bars [31] ; Elisabeth J,Leehr [17] ; Meng,Li [22] ; Elizabeth T C,Lippard [45] ; Carlos,Lopez-Jaramillo [46] ; Ivan I,Maximov [47] ; Andrew M,McIntosh [48] ; Katie A,McLaughlin [49] ; Sean R,McWhinney [11] ; Susanne,Meinert [50] ; Elisa,Melloni [20] ; Philip B,Mitchell [51] ; Benson,Mwangi [52] ; Igor,Nenadić [13] ; Stener,Nerland [53] ; Emilie,Olie [28] ; Victor,Ortiz-García de la Foz [14] ; Pedro M,Pan [54] ; Fabricio,Pereira [55] ; Fabrizio,Piras [16] ; Federica,Piras [16] ; Sara,Poletti [20] ; Andrew E,Reineberg [56] ; Gloria,Roberts [51] ; Rafael,Romero-García [57] ; Matthew D,Sacchet [58] ; Giovanni A,Salum [59] ; Anca-Larisa,Sandu [60] ; Carl M,Sellgren [61] ; Eiji,Shimizu [62] ; Harry R,Smolker [63] ; Jair C,Soares [52] ; J Douglas,Steele [64] ; Frederike,Stein [13] ; Dan J,Stein [65] ; Benjamin,Straube [13] ; Lea,Teutenberg [13] ; Florian,Thomas-Odenthal [13] ; Paula,Usemann [13] ; Romain,Valabregue [66] ; Johanna,Valencia-Echeverry [46] ; Gerd,Wagner [67] ; Gordon,Waiter [60] ; Martin,Walter [22] ; Heather C,Whalley [68] ; Mon-Ju,Wu [52] ; Tony T,Yang [69] ; Carlos A,Zarate [15] ; Andre,Zugman [70] ; Giovana B,Zunta-Soares [52] ; Kees,van Heeringen [71] ; Sanne J H,van Rooij [33] ; Nic,van der Wee [72] ; Steven,van der Werff [72] ; Paul M,Thompson [9] ; Hilary P,Blumberg [73] ; Anne-Laura,van Harmelen [74] ; Miguel E,Rentería [3] ; Neda,Jahanshad [9] ; ENIGMA Suicidal Thoughts and Behaviours Consortium [75] ; Lianne,Schmaal
作者单位: Orygen, Parkville, VIC, Australia. laurasvanvelzen@gmail.com.;Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia. laurasvanvelzen@gmail.com. [1] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.;Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.;DZPG (German Center for Mental Health), partner site Halle/Jena/Magdeburg, Halle/Jena/Magdeburg, Germany. [2] QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.;School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia. [3] Institute for Mental Health, School of Psychology, University of Birmingham, Birmingham, UK.;Department of Psychiatry, University of Cambridge, Cambridge, UK. [4] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. [5] Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia.;Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia. [6] Orygen, Parkville, VIC, Australia.;Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia.;Department of Psychology, Education and Child Studies, Erasmus University Rotterdam, Rotterdam, the Netherlands. [7] Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia.;School of Psychology, Deakin University, Melbourne, VIC, Australia. [8] Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA. [9] QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.;School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.;Regeneron Genetics Center, Tarrytown, NY, USA. [10] Department of Psychiatry, Dalhousie University, Halifax, NS, Canada. [11] Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.;Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.;Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden. [12] Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.;Center for Mind, Brain, and Behavior (CMBB), University of Marburg, Marburg, Germany. [13] Department of Psychiatry. Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria, Santander, Spain. [14] Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. [15] Laboratory of Neuropsychiatry, Clinical Neuroscience and Neurorehabilitation Department, Santa Lucia Foundation IRCCS, Rome, Italy. [16] Institute for Translational Psychiatry, University of Münster, Münster, Germany. [17] Department of Psychiatry and Behavioral Sciences, University of Minnesota Medical School, Minneapolis, MN, USA. [18] Clinic for Radiology, University Hospital Münster, Münster, Germany. [19] Division of Neuroscience, Psychiatry and Psychobiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy. [20] Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany. [21] Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.;DZPG (German Center for Mental Health), partner site Halle/Jena/Magdeburg, Halle/Jena/Magdeburg, Germany. [22] Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.;Center for Mind, Brain, and Behavior (CMBB), University of Marburg, Marburg, Germany.;Institute of Behavioral Sciences, Feinstein Institutes for Medical Research, Manhasset, NY, USA. [23] Instituto de Biomedicina de Sevilla (IBiS)/HUVR/CSIC/Universidad de Sevilla. CIBERSAM (ISCIII), Seville, Spain.;Mental Health Service, Hospital Universitario Virgen del Rocío, Sevilla, Spain. [24] Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.;Department of Medical Sciences, Psychiatry, Uppsala University, Uppsala, Sweden. [25] MOODS Team, INSERM 1018, CESP, Université Paris-Saclay, Faculté de Médecine Paris-Saclay, Service Hospitalo-Universitaire de Psychiatrie de Bicêtre, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Saclay, Hôpital de Bicêtre, Le Kremlin Bicêtre, F-94275, France. [26] Department of Biomedical Sciences, Florida State University, Tallahassee, FL, USA. [27] Department of Emergency Psychiatry and Acute Care, Lapeyronie Hospital, CHU Montpellier, Montpellier, France.;IGF, Univ. Montpellier, CNRS, INSERM, Montpellier, France. [28] Institute for Molecular Bioscience, the University of Queensland, St Lucia, QLD, Australia.;Sorbonne University, Paris Brain Institute - ICM, CNRS, Inria, Inserm, AP-HP, Hôpital de la Pitié Salpêtrière, F-75013, Paris, France. [29] Instituto de Biomedicina de Sevilla (IBiS)/HUVR/CSIC/Universidad de Sevilla. CIBERSAM (ISCIII), Seville, Spain.;Mental Health Service, Hospital Universitario Virgen del Rocío, Sevilla, Spain.;Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III (CIBERSAM), Madrid, Spain. [30] Institut d'Imagerie Fonctionnelle Humaine, I2FH, Department of Neuroradiology, Gui de Chauliac Hospital and University of Montpellier, Montpellier, France.;Department of Neuroradiology, Gui de Chauliac Hospital and University of Montpellier, Montpellier, France. [31] Center for Neurobehavioral Genetics,Semel Institute for Neuroscience and Behavior David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.;Research Group in Psychiatry GIPSI, Department of Psychiatry, Faculty of Medicine, Universidad de Antioquia, Medellin, Colombia. [32] Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA. [33] Institute for Behavioral Genetics and Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA. [34] Department of Psychology, Stanford University, Stanford, CA, 94305, USA. [35] Department of Psychiatry & Neuroscience Institute, University of Cape Town, Cape Town, South Africa. [36] Department of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA. [37] The University of Sydney, Sydney, Australia. [38] Research Center for Child Mental Development, Chiba University, Chiba, Japan.;United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University, Chiba University and University of Fukui, Fukui, Japan. [39] Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.;Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, USA. [40] Research Center for Child Mental Development, Chiba University, Chiba, Japan.;Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba, Japan. [41] Østfold University College Department of Education, ICT and Learning, Halden, Norway.;Universidade Federal de São Paulo, São Paulo, Brazil. [42] Faculty of Medicine, University Paris-Saclay, Le Kremlin-Bicetre, France.;Clinical Department of Psychiatry and Addictology, Paul Brousse Hospital, APHP, Villejuif, France.;Department of psychiatry, McGill University, Montreal, Canada. [43] Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.;Department of Psychiatry, University Hospital Bonn, Bonn, Germany. [44] Department of Psychiatry and Behavioral Sciences, Dell Medical School, University of Texas at Austin, Austin, TX, USA.;University of Texas at Austin, Austin, TX, USA. [45] Research Group in Psychiatry GIPSI, Department of Psychiatry, Faculty of Medicine, Universidad de Antioquia, Medellin, Colombia. [46] Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.;Department of Health and Functioning, Western Norway University of Applied Sciences, Bergen, Norway. [47] Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK. [48] Ballmer Institute for Children's Behavioral Health, University of Oregon, Eugene, OR, USA.;Department of Psychology, Harvard University, Cambridge, MA, USA. [49] Institute for Translational Psychiatry, University of Münster, Münster, Germany.;Institute for Translational Neuroscience, University of Münster, Münster, Germany. [50] Discipline of Psychiatry and Mental Health, School of Clinical Medicine, University of New South Wales, Sydney, Australia. [51] Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.;UTHealth Houston School of Behavioral Health Sciences, Houston, TX, USA. [52] Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.;Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway. [53] Universidade Federal de São Paulo, São Paulo, Brazil. [54] MIPA, Université de Nîmes, Nimes, France.;Division for clinical research and innovation, University Hospital Center of Nimes, Nimes, France. [55] Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA. [56] Department of Psychiatry, University of Cambridge, Cambridge, UK.;Instituto de Biomedicina de Sevilla (IBiS)/HUVR/CSIC/Universidad de Sevilla. CIBERSAM (ISCIII), Seville, Spain. [57] Meditation Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. [58] Child Mind Institute, New York, NY, USA.;Universidade Federal do Rio Grande do Sul, Hospital de Clinicas de Porto Alegre - Porto Alegre, Porto Alegre, Brazil. [59] Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK. [60] Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.;Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden. [61] Research Center for Child Mental Development, Chiba University, Chiba, Japan.;United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University, Chiba University and University of Fukui, Fukui, Japan.;Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba, Japan. [62] Institute for Cognitive Science, University of Colorado Boulder, Boulder, CO, USA. [63] Division of Imaging Science and Technology, Medical School, University of Dundee, Dundee, UK. [64] SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry & Neuroscience Institute, University of Cape Town, Cape Town, South Africa. [65] Institut du Cerveau et de la Moelle épinière, ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Paris, France.;Centre de Neuro-Imagerie de Recherche, CENIR, ICM, Paris, France. [66] Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.;Center for Intervention and Research on adaptive and maladaptive brain Circuits underlying mental health (C-I-R-C), Jena-Magdeburg-Halle, Jena, Germany. [67] Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.;Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK. [68] Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA. [69] National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. [70] Ghent University, Ghent, Belgium. [71] Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.;Leiden Institute for Brain and Cognition. Leiden University Medical Center, Leiden, The Netherlands. [72] Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.;Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA.;Child Study Center, Yale School of Medicine, New Haven, CT, USA. [73] Department of Psychiatry, University of Cambridge, Cambridge, UK.;Education and Child Studies, Leiden University, Leiden, the Netherlands. [74] Orygen, Parkville, VIC, Australia.;Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia. [75]
DOI 10.1038/s41398-025-03602-1
PMID 41136374
发布时间 2025-10-28
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