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Engineering Cortical Networks: An Open Platform for Controlled Human Circuit Formation and Synaptic Analysis In Vitro.

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第一作者： Pacharaporn,Suklai

第一单位： Department of Basic and Clinical Neuroscience, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, SE5 9RX, UK.;UK Dementia Research Institute at King's College London, London, SE5 9RX, UK.;The Francis Crick Institute, London, NW1 1AT, UK.

作者： Pacharaporn,Suklai ^[1] ; Taylor,Minckley ^[1] ; Cathleen,Hagemann ^[1] ; Karolina,Faber ^[2] ; Rosalind,Norkett ^[3] ; Ludovica,Guetta ^[1] ; Kelly,O'Toole ^[1] ; Bethany,Geary ^[2] ; Michael J,Devine ^[4] ; Andrea,Serio ^[1]

作者单位： Department of Basic and Clinical Neuroscience, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, SE5 9RX, UK.;UK Dementia Research Institute at King's College London, London, SE5 9RX, UK.;The Francis Crick Institute, London, NW1 1AT, UK. ^[1] Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK. ^[2] The Francis Crick Institute, London, NW1 1AT, UK. ^[3] The Francis Crick Institute, London, NW1 1AT, UK.;Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK. ^[4]

关键词 bioengineering in vitro modelling neural circuits synapses

医学主题词人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);突触(Synapses);神经网(Nerve Net);神经元(Neurons);大脑皮质(Cerebral Cortex);组织工程(Tissue Engineering)

DOI 10.1002/adhm.202500857

PMID 41137417

发布时间 2025-12-10

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