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Anxiety induced by systemic inflammation involves microglial engulfing of nucleus accumbens inputs and diminished excitability of dopamine D1 receptor neurons.

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第一作者： Shingo,Nakajima

第一单位： Centre de Recherche du CHUM and Université de Montréal, Montréal, QC H3T1J4, Canada.

作者： Shingo,Nakajima ^[1] ; Anita,Kabahizi ^[2] ; Solal,Aubailly ^[2] ; Samar,Naili-Douaouda ^[2] ; Akari,Tomita ^[1] ; Anthony,Bosson ^[1] ; Thierry,Alquier ^[3] ; Ciaran,Murphy-Royal ^[2] ; Stephanie,Fulton ^[4]

作者单位： Centre de Recherche du CHUM and Université de Montréal, Montréal, QC H3T1J4, Canada. ^[1] Centre de Recherche du CHUM and Université de Montréal, Montréal, QC H3T1J4, Canada; Departments of Neuroscience and Université de Montréal, Montréal, QC H3T1J4, Canada. ^[2] Centre de Recherche du CHUM and Université de Montréal, Montréal, QC H3T1J4, Canada; Departments of Medicine and Université de Montréal, Montréal, QC H3T1J4, Canada. ^[3] Centre de Recherche du CHUM and Université de Montréal, Montréal, QC H3T1J4, Canada; Departments of Nutrition and Université de Montréal, Montréal, QC H3T1J4, Canada. Electronic address: stephanie.fulton@umontreal.ca. ^[4]

关键词 D1 receptor Endotoxemia Medium spiny neurons Microglia pruning Neuroinflammation Ventral striatum