首页> Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer> Phase 2 Study of Amivantamab Plus Lazertinib in Previously Treated Patients With EGFR-Mutant Lung Cancers With Brain and Leptomeningeal Metastases.

Phase 2 Study of Amivantamab Plus Lazertinib in Previously Treated Patients With EGFR-Mutant Lung Cancers With Brain and Leptomeningeal Metastases.

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第一作者： Monica F,Chen

第一单位： Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York.

作者： Monica F,Chen ^[1] ; Jake June-Koo,Lee ^[2] ; Noura J,Choudhury ^[3] ; Angela B,Hui ^[4] ; Mark Y,Jeng ^[2] ; Jennifer,Zheng ^[2] ; Rania G,Aly ^[5] ; Neil,Sielski ^[6] ; Linda,Ahn ^[2] ; Amanda,Pupo ^[2] ; Monica C,Nesselbush ^[7] ; Isabel,Jabara ^[7] ; Jessica A,Wilcox ^[6] ; Bianca D,Santomasso ^[6] ; Andrew L,Lin ^[6] ; Lauren,Schaff ^[6] ; Jamie E,Chaft ^[1] ; Gregory J,Riely ^[1] ; Mark G,Kris ^[1] ; Andrea,Arfe ^[8] ; Soo-Ryum,Yang ^[5] ; Robert J,Young ^[9] ; Maximilian,Diehn ^[10] ; Adrienne,Boire ^[11] ; Helena A,Yu ^[12]

作者单位： Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York. ^[1] Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. ^[2] Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois. ^[3] Department of Radiation Oncology, Stanford University, Stanford, California. ^[4] Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York. ^[5] Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York. ^[6] Department of Radiation Oncology, Stanford University, Stanford, California; Department of Biology, Stanford University, Stanford, California. ^[7] Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York. ^[8] Department of Radiology, Memorial Sloan Kettering Cancer Center, New York City, New York. ^[9] Department of Radiation Oncology, Stanford University, Stanford, California; Department of Biology, Stanford University, Stanford, California; Stanford Cancer Institute, Stanford University, Stanford, California. ^[10] Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York; Human Oncology & Pathogenesis, Memorial Sloan Kettering Cancer Center, New York, New York. ^[11] Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York. Electronic address: yuh@mskcc.org. ^[12]

关键词 Brain metastases EGFR Leptomeningeal disease Targeted therapy