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Metabolomic profiling reveals distinct lipid signatures in progressive versus stable fibrotic lung disease.

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第一作者： Faizan,Faizee

第一单位： Pulmonary Disease and Critical Care Medicine, Corewell Health East, Royal Oak, MI, 48073, USA. Faizee.faizy@gmail.com.;Corewell Health East, William Beaumont University Hospital, Royal Oak, MI, 48073, USA. Faizee.faizy@gmail.com.

作者： Faizan,Faizee ^[1] ; Zachary,Smith ^[2] ; Olga,Gomez ^[3] ; Zaid,Alnabulsi ^[3] ; Glenn,Pottmeyer ^[3] ; Nadia,Ashrafi ^[4] ; Romana Ashrafi,Mimi ^[4] ; Vilija,Lomeikaite ^[5] ; Miglė,Gabrielaitė ^[5] ; Karolis,Krinickis ^[5] ; Juozas,Gordevičius ^[5] ; Ali,Yilmaz ^[6] ; Edward,Castillo ^[7] ; Stewart F,Graham ^[6] ; Girish B,Nair ^[8]

作者单位： Pulmonary Disease and Critical Care Medicine, Corewell Health East, Royal Oak, MI, 48073, USA. Faizee.faizy@gmail.com.;Corewell Health East, William Beaumont University Hospital, Royal Oak, MI, 48073, USA. Faizee.faizy@gmail.com. ^[1] Corewell Health East, William Beaumont University Hospital, Royal Oak, MI, 48073, USA. zachary.smith4@corewellhealth.org.;Department of Internal Medicine, Corewell Health East, Royal Oak, MI, 48073, USA. zachary.smith4@corewellhealth.org. ^[2] Pulmonary Disease and Critical Care Medicine, Corewell Health East, Royal Oak, MI, 48073, USA.;Corewell Health East, William Beaumont University Hospital, Royal Oak, MI, 48073, USA. ^[3] Corewell Health East, William Beaumont University Hospital, Royal Oak, MI, 48073, USA.;Metabolomics Department, Corewell Health Research Institute, Royal Oak, MI, 48073, USA. ^[4] VUGENE, LLC, 625 Kenmoor Ave Suite, 301 PMB 96578, Grand Rapids, MI, 49546, USA. ^[5] Corewell Health East, William Beaumont University Hospital, Royal Oak, MI, 48073, USA.;Metabolomics Department, Corewell Health Research Institute, Royal Oak, MI, 48073, USA.;Oakland University-William Beaumont School of Medicine, Rochester, MI, 48309, USA. ^[6] The University of Texas at Austin, Austin, USA. ^[7] University of Kentucky College of Medicine, Lexington, USA. Girish.nair@uky.edu. ^[8]

关键词 1H NMR Biocrates Quant 500 XL Idiopathic pulmonary fibrosis Interstitial lung disease Lung fibrosis Mass spectrometry Metabolomics Progressive pulmonary fibrosis