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Reproducible Human Neural Circuits Printed with Single-Cell Precision Reveal the Functional Roles of Ephaptic Coupling.

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第一作者： Johannes,Striebel

第一单位： Faculty of Medicine, Department of Ophthalmology, University of Bonn, Ernst-Abbe-Str. 2 53127 Bonn, Germany.;University Hospital Bonn, Venusberg-Campus 153127 Bonn, Germany.

作者： Johannes,Striebel ^[1] ; Rouhollah,Habibey ^[1] ; Daniel,Wendland ^[2] ; Helge,Gehring ^[3] ; Elizaveta,Podoliak ^[1] ; Julia S,Pawlick ^[1] ; Kritika,Sharma ^[1] ; Alex H M,Ng ^[4] ; Wolfram,Pernice ^[2] ; Volker,Busskamp ^[1]

作者单位： Faculty of Medicine, Department of Ophthalmology, University of Bonn, Ernst-Abbe-Str. 2 53127 Bonn, Germany.;University Hospital Bonn, Venusberg-Campus 153127 Bonn, Germany. ^[1] Institute of Physics and Center for Nanotechnology, University of Münster, Heisenbergstraße 1148149 Münster, Germany.;Kirchhoff-Institute for Physics, University of Heidelberg, Im Neuenheimer Feld 227 69120 Heidelberg, Germany. ^[2] Institute of Physics and Center for Nanotechnology, University of Münster, Heisenbergstraße 1148149 Münster, Germany. ^[3] Department of Genetics, Blavatnik Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.;Wyss Institute for Biologically Inspired Engineering at Harvard University, 201 Brookline Avenue, Boston, Massachusetts 02215, United States. ^[4]

关键词 direct laser writing ephaptic coupling in vitro stem cell-derived neuronal networks microelectrode array microscaffolds reproducible neuronal network formation single-cell resolution

医学主题词人类(Humans);神经元(Neurons);神经网(Nerve Net);单细胞分析(Single-Cell Analysis)

DOI 10.1021/acsnano.5c11482

PMID 41139300

发布时间 2025-11-15

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准确一般字义偏差语意偏离译文作用小提交