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Microenvironment-responsive size-adaptive nanoparticles: hyaluronidase/acid/NIR light activation for deep-penetration trimodal therapy.

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第一作者： Hao,Wu

第一单位： Engineering Research Center for Pharmaceuticals and Equipments of Sichuan Province, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, 610106, PR China.;Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-er-qiao Road, Chengdu, 610072, PR China.

作者： Hao,Wu ^[1] ; Hongping,Li ^[2] ; Li,Li ^[2] ; Yungchang,Chen ^[3] ; Hongping,Yang ^[2] ; Chongxiu,Shi ^[2] ; Wenhao,Li ^[2] ; Li,Ye ^[2] ; Liming,Zhu ^[2] ; Gang,He ^[2] ; Suling,Luo ^[3] ; Jing,Tao ^[2] ; Ling,Mei ^[2] ; Xue,Shen ^[2]

作者单位： Engineering Research Center for Pharmaceuticals and Equipments of Sichuan Province, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, 610106, PR China.;Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-er-qiao Road, Chengdu, 610072, PR China. ^[1] Engineering Research Center for Pharmaceuticals and Equipments of Sichuan Province, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, 610106, PR China. ^[2] Department of Medical Oncology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, and School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610041, PR China. ^[3]

关键词 Chemo-phototherapy Fission HA HSA Size-adaptive Targeted delivery

DOI 10.1016/j.mtbio.2025.102384

PMID 41142431

发布时间 2025-10-29

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Materials today. Bio

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Microenvironment-responsive size-adaptive nanoparticles: hyaluronidase/acid/NIR light activation for deep-penetration trimodal therapy.

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Microenvironment-responsive size-adaptive nanoparticles: hyaluronidase/acid/NIR light activation for deep-penetration trimodal therapy.

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