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Cilofexor in non-cirrhotic primary sclerosing cholangitis (PRIMIS): a randomised, double-blind, multicentre, placebo-controlled, phase 3 trial.

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第一作者: Michael,Trauner
第一单位: Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria. Electronic address: michael.trauner@meduniwien.ac.at.
作者单位: Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria. Electronic address: michael.trauner@meduniwien.ac.at. [1] Division of Digestive Health and Liver Diseases and Schiff Center for Liver Diseases, University of Miami Miller School of Medicine, Miami, FL, USA. [2] Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan. [3] Center for Liver Diseases, Inova Fairfax Hospital, Falls Church, VA, USA. [4] The Sheila Sherlock Liver Centre and UCL Institute of Liver and Digestive Health, Royal Free Hospital, London, UK. [5] Institute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK. [6] Division of Gastroenterology, Department of Medicine, Turku University Hospital, Turku, Finland. [7] Department of Hepatology and Liver Transplantation, California Pacific Medical Center, San Francisco, CA, USA. [8] Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan. [9] Division of Gastroenterology and Liver Unit, University of Alberta, Edmonton, AB, Canada. [10] Division of Gastroenterology and Hepatology, University of Virginia Health System, Charlottesville, VA, USA. [11] School of Clinical Medicine, Faculty of Medicine, UNSW, Sydney, Australia; Department of Gastroenterology and Hepatology, St Vincent's Hospital, Sydney, NSW, Australia. [12] Clinic of Gastroenterology, Helsinki University, Helsinki University Hospital, Helsinki, Finland. [13] Division of Gastroenterology and Hepatology, University of Utah Spencer Fox Eccles School of Medicine, Salt Lake City, UT, USA. [14] Department of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, USA; Wayne State University School of Medicine, Detroit, MI, USA. [15] Gastroenterologisch-Hepatologisches MVZ Kiel, Kiel, Germany. [16] Division of Gastroenterology, Center for Autoimmune Liver Diseases, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), IRCCS Fondazione San Gerardo dei Tintori, Monza, Italy; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy. [17] Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA. [18] Gilead Sciences, Foster City, CA, USA. [19] Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, CA, USA. [20]
DOI 10.1016/S2468-1253(25)00208-0
PMID 41173015
发布时间 2025-12-30
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The lancet. Gastroenterology & hepatology

The lancet. Gastroenterology & hepatology

2026年11卷1期

46-58页

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