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Jianpi-huayu Decotion regulates TREM1/DAP12 pathway to improve the immunosuppressive tumor microenvironment and enhance the anti-hepatocellular carcinoma effect of PD-1 inhibitors.

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第一作者: Ruiwei,Yao
第一单位: State Key Laboratory of Traditional Chinese Medicine Syndrome/Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China; Cancer Center, Shenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine, Shenzhen, China.
作者: Ruiwei,Yao [1] ; Ying,Zhang [2] ; Wusheng,Yu [3] ; Xinqiu,Chen [4] ; Hanqian,Shi [4] ; Rui,Luo [4] ; Chongkai,Fang [5] ; Xilin,Zhao [6] ; Xiaoyu,Zhu [4] ; Yongheng,Lai [4] ; Shanshan,Xiao [7] ; Yuan,Chen [8] ; Jingtao,Zhang [9] ; Chong,Zhong [10]
作者单位: State Key Laboratory of Traditional Chinese Medicine Syndrome/Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China; Cancer Center, Shenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine, Shenzhen, China. [1] Shenzhen Bao'an Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, Shenzhen, China. [2] Department of Hepatobiliary and Pancreatic Surgery, The Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Dongguan, China. [3] Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. [4] State Key Laboratory of Traditional Chinese Medicine Syndrome/Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China. [5] State Key Laboratory of Traditional Chinese Medicine Syndrome/Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Biliary-Pancreatic Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. [6] Department of Pathology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. [7] Animal Laboratory Center, Guangzhou University of Chinese Medicine, Guangzhou, China. Electronic address: chenyuan1@gzucm.edu.cn. [8] The Eighth Clinical Medical College, Guangzhou University of Chinese Medicine, Foshan, China; Department of Cancer Center, Foshan Hospital of Traditional Chinese Medicine, Foshan, China. Electronic address: jitozhang@163.com. [9] State Key Laboratory of Traditional Chinese Medicine Syndrome/Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Biliary-Pancreatic Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, China. Electronic address: zhongchong1732@gzucm.edu.cn. [10]
DOI 10.1016/j.jep.2025.120846
PMID 41177238
发布时间 2025-11-24
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