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Human B-lymphopoiesis: Clinical challenges in B cell reconstitution and advances in in vitro modeling.

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第一作者： Franziska Maria,Schmidt

第一单位： Division of Clinical and Experimental Immunology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

作者： Franziska Maria,Schmidt ^[1] ; Marta,Rizzi ^[2]

作者单位： Division of Clinical and Experimental Immunology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria. ^[1] Division of Clinical and Experimental Immunology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria; Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany. Electronic address: marta.rizzi@meduniwien.ac.at. ^[2]

关键词 B lymphocytes BM Feeder-free Modelling Reconstitution iPSCs culture in vitro

医学主题词人类(Humans);淋巴细胞生成(Lymphopoiesis);B-淋巴细胞(B-Lymphocytes);动物(Animals);小鼠(Mice);造血干细胞(Hematopoietic Stem Cells);细胞分化(Cell Differentiation)

DOI 10.1016/j.imlet.2025.107106

PMID 41192681

发布时间 2025-12-03

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