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Synthesis, in vitro, and in silico studies of 4-chlorophenyl-sulfonyl Indole based thiosemicarbazones as competitive α-glucosidase inhibitors.

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第一作者： Iqra,Naseer

第一单位： Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan.

作者： Iqra,Naseer ^[1] ; Saeed,Ullah ^[2] ; Zahra,Batool ^[1] ; Mariya,Al-Rashida ^[3] ; Talha,Islam ^[3] ; Ajmal,Khan ^[4] ; Javid,Hussain ^[5] ; Ahmed,Al-Harrasi ^[6] ; Zahid,Shafiq ^[7] ; Ahmed Mohamed,Tawfeek ^[8] ; Mohammad Shahidul,Islam ^[9]

作者单位： Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan. ^[1] Department of Biology and Biochemistry, University of Houston, Houston, TX, 77004, USA. ^[2] Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan. ^[3] Department of Chemical and Biological Engineering, College of Engineering, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.;Natural and Medical Sciences Research Centre, University of Nizwa, Birkat Al Mauz, PC 616, P.O. Box 33, Nizwa, Sultanate of Oman. ^[4] Department of Biological Sciences and Chemistry, University of Nizwa, Nizwa, Oman. ^[5] Natural and Medical Sciences Research Centre, University of Nizwa, Birkat Al Mauz, PC 616, P.O. Box 33, Nizwa, Sultanate of Oman. aharrasi@unizwa.edu.om. ^[6] Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan. zahidshafiq@bzu.edu.pk. ^[7] Department of Chemistry, College of Science, King Saud University, P. O. Box 2455, Riyadh, 11451, Saudi Arabia. ^[8] Department of Chemistry, College of Science, King Saud University, P. O. Box 2455, Riyadh, 11451, Saudi Arabia. mislam@ksu.edu.sa. ^[9]

关键词 4-chlorophenyl-sulfonyl indole Glucosidase In silico Kinetics Molecular docking