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The aryl hydrocarbon receptor inhibits antigen presentation to promote progression of pancreatic ductal adenocarcinoma.

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第一作者： Wentong,Mei

第一单位： Department of General Surgery, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Beijing, China; Department of Gastrointestinal Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China.

作者： Wentong,Mei ^[1] ; Yixuan,Ding ^[2] ; Chunjing,Bian ^[2] ; Yuchen,Jia ^[2] ; Chang,Qu ^[2] ; Zhen,Fang ^[2] ; Jie,Li ^[2] ; Shuang,Liu ^[2] ; Haichen,Sun ^[2] ; Xiaoqing,Xu ^[3] ; Jia,Li ^[4] ; Fei,Li ^[5]

作者单位： Department of General Surgery, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Beijing, China; Department of Gastrointestinal Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China. ^[1] Department of General Surgery, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Beijing, China. ^[2] Department of General Surgery, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Beijing, China. Electronic address: xiaoqingxu@cams.cn. ^[3] Department of General Surgery, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Beijing, China. Electronic address: lij@xwhosp.org. ^[4] Department of General Surgery, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Beijing, China. Electronic address: feili36@ccmu.edu.cn. ^[5]

关键词 Aryl hydrocarbon receptor (AhR)Chromatin accessibility MHC-Ⅰ Pancreatic ductal adenocarcinoma (PDAC)Protein arginine methyltransferase 5 (PRTM5)

DOI 10.1016/j.jare.2025.10.079

PMID 41203070

发布时间 2025-11-12

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