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Immune correlates analysis of antibody responses against SARS-CoV-2 variants in the ENSEMBLE vaccine efficacy trial.

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第一作者: Alex,Luedtke
第一单位: Department of Statistics, University of Washington, Seattle, WA 98195, USA.;Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.;Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.
作者: Alex,Luedtke [1] ; Youyi,Fong [2] ; Lars,van der Laan [3] ; Fei,Heng [4] ; Ying,Huang [2] ; Yiwen,Lu [5] ; Chenchen,Yu [5] ; Lindsay N,Carpp [5] ; Sanne,Roels [6] ; Mathieu,Le Gars [7] ; Griet A,Van Roey [7] ; Daniel J,Stieh [7] ; Ilse,Van Dromme [6] ; Avi,Kenny [8] ; Marco,Carone [9] ; Ollivier,Hyrien [2] ; Victor,Ayala [10] ; Lakshmi,Jayashankar [10] ; Flora,Castellino [10] ; Obrimpong,Amoa-Awua [11] ; Manjula,Basappa [11] ; Britta,Flach [11] ; Bob C,Lin [11] ; Christopher,Moore [11] ; Mursal,Naisan [11] ; Muhammed,Naqvi [11] ; Sandeep,Narpala [11] ; Sarah,O'Connell [11] ; Allen,Mueller [11] ; Leo,Serebryannyy [11] ; Mike,Castro [11] ; Jennifer,Wang [11] ; Gabrielle,Dziubla [11] ; April K,Randhawa [5] ; Michele P,Andrasik [5] ; Jenny,Hendriks [7] ; Carla,Truyers [6] ; Frank,Struyf [6] ; Hanneke,Schuitemaker [7] ; Macaya,Douoguih [7] ; James G,Kublin [5] ; Lawrence,Corey [12] ; Kathleen M,Neuzil [13] ; Linda-Gail,Bekker [14] ; Nigel,Garrett [15] ; Sandra W,Cardoso [16] ; Patrice,DelaFontaine [17] ; Craig A,Magaret [5] ; Johan,Vingerhoets [6] ; Martin,Casapia [18] ; Marcelo H,Losso [19] ; Susan J,Little [20] ; Aditya,Gaur [21] ; Edith,Swann [22] ; Christos J,Petropoulos [23] ; Adrian B,McDermott [11] ; Jerald,Sadoff [7] ; Glenda E,Gray [24] ; Beatriz,Grinsztejn [16] ; Paul A,Goepfert [25] ; Dean,Follmann [26] ; Pavitra,Roychoudhury [27] ; Alexander L,Greninger [27] ; Richard A,Koup [11] ; Ruben O,Donis [10] ; Peter B,Gilbert [2] ; Immune Assays Team ; Coronavirus Vaccine Prevention Network (CoVPN)/ENSEMBLE Team ; United States Government (USG)/CoVPN Biostatistics Team
作者单位: Department of Statistics, University of Washington, Seattle, WA 98195, USA.;Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.;Department of Biostatistics, University of Washington, Seattle, WA 98195, USA. [1] Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.;Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.;Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA. [2] Department of Statistics, University of Washington, Seattle, WA 98195, USA.;Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA. [3] Department of Mathematics and Statistics, University of North Florida, Jacksonville, FL 32224, USA. [4] Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA. [5] Johnson & Johnson Innovative Medicine, Janssen Pharmaceutica NV, 2340 Beerse, Belgium. [6] Johnson & Johnson Innovative Medicine, Janssen Vaccines & Prevention B.V., 2301 Leiden, the Netherlands. [7] Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27710, USA.;Global Health Institute, Duke University, Durham, NC 27710, USA. [8] Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA. [9] Biomedical Advanced Research and Development Authority, Administration for Strategic Preparedness and Response, U.S. Department of Health and Human Services, Washington, DC 20201, USA. [10] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. [11] Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.;Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA. [12] Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA. [13] Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, Cape Town 7925, South Africa.;Department of Medicine, University of Cape Town and Groote Schuur Hospital, Observatory, Cape Town 7925, South Africa.;Desmond Tutu HIV Centre, University of Cape Town, Cape Town 7705, South Africa. [14] Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.;Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban 4041, South Africa. [15] Evandro Chagas National Institute of Infectious Diseases-Fundação Oswaldo Cruz, Rio de Janeiro CEP 21.040-900, Brazil. [16] Department of Medicine, Tulane University, New Orleans, LA 70112, USA.;Department of Physiology, Tulane University, New Orleans, LA 70112, USA.;Department of Pharmacology, Tulane University, New Orleans, LA 70112, USA. [17] Facultad de Medicina Humana, Universidad Nacional de la Amazonia Peru, Iquitos 16004, Peru. [18] Hospital General de Agudos José María Ramos Mejia, Buenos Aires 1221, Argentina. [19] Division of Infectious Diseases, University of California, San Diego, La Jolla, CA 92037, USA. [20] Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. [21] Vaccine Research Program, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. [22] LabCorp-Monogram Biosciences, South San Francisco, CA 94080, USA. [23] Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa.;South African Medical Research Council, Cape Town 7505, South Africa. [24] Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA. [25] Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. [26] Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.;Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. [27]
DOI 10.1016/j.isci.2025.113660
PMID 41210956
发布时间 2025-11-12
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