换一批UPF1 alleviates myocardial ischemia/reperfusion injury via suppressing NLRP3-mediated cardiomyocyte pyroptosis by inhibiting KLF6/TXNIP axis.
第一作者：
Wei,Yan
第一单位：
Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Central South University, Changsha, Hunan Province, China; Extracorporeal Life Support Center of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan Province, China.
作者：
医学主题词
动物(Animals);心肌再灌注损伤(Myocardial Reperfusion Injury);小鼠(Mice);肌细胞, 心脏(Myocytes, Cardiac);男(雄)性(Male);反式激活因子类(Trans-Activators);载体蛋白质类(Carrier Proteins);细胞系(Cell Line);小鼠, 近交C57BL(Mice, Inbred C57BL);信号传导(Signal Transduction);疾病模型, 动物(Disease Models, Animal);炎性体(Inflammasomes);硫氧还蛋白质类(Thioredoxins)
DOI
10.1016/j.intimp.2025.115789
PMID
41242274
发布时间
2025-12-09
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