首页> Journal of ethnopharmacology> Dendropanax proteus root and its major bio-phytochemicals alleviate rheumatoid arthritis by inhibiting TLR4/CLEC1B/PI3K/Akt/NF-κB pathways: proteomics, metabolomics, collagen-induced arthritis rats, MH7A cells, molecular docking, and molecular dynamic simulation.

Dendropanax proteus root and its major bio-phytochemicals alleviate rheumatoid arthritis by inhibiting TLR4/CLEC1B/PI3K/Akt/NF-κB pathways: proteomics, metabolomics, collagen-induced arthritis rats, MH7A cells, molecular docking, and molecular dynamic simulation.

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第一作者： Li,Yang

第一单位： Jiangxi University of Chinese Medicine, Nanchang, 330004, PR China. Electronic address: yangli07971@163.com.

作者： Li,Yang ^[1] ; Yating,Yang ^[2] ; Qihui,Wang ^[3] ; Jian,Liang ^[4] ; Shengyuan,Zhang ^[5] ; Hua,Nie ^[6] ; Huang,Zeng ^[7] ; Junwei,He ^[8]

作者单位： Jiangxi University of Chinese Medicine, Nanchang, 330004, PR China. Electronic address: yangli07971@163.com. ^[1] Jiangxi University of Chinese Medicine, Nanchang, 330004, PR China. Electronic address: yang231128@163.com. ^[2] Jiangxi University of Chinese Medicine, Nanchang, 330004, PR China. Electronic address: 13237975196@163.com. ^[3] Jiangxi University of Chinese Medicine, Nanchang, 330004, PR China. Electronic address: Ocean719@163.com. ^[4] Guangdong Provincial Key Laboratory of Conservation and Precision Utilization of Characteristic Agricultural Resources in Mountainous Aeras, Jiaying University, Meizhou, 514015, PR China. Electronic address: mcdullzhang@163.com. ^[5] Guangdong Provincial Key Laboratory of Conservation and Precision Utilization of Characteristic Agricultural Resources in Mountainous Aeras, Jiaying University, Meizhou, 514015, PR China. Electronic address: niehua@jyu.edu.cn. ^[6] Guangdong Provincial Key Laboratory of Conservation and Precision Utilization of Characteristic Agricultural Resources in Mountainous Aeras, Jiaying University, Meizhou, 514015, PR China. Electronic address: zengh39@mail2.sysu.edu.cn. ^[7] Jiangxi University of Chinese Medicine, Nanchang, 330004, PR China. Electronic address: hjwjn2008@163.com. ^[8]

关键词 Dendropanax proteus root Rheumatoid arthritis Syringin and chlorogenic acid TLR4/CLEC1B/PI3K/Akt/NF-κB pathways