Identification and Structural Characterization of Degradation Products of Tivozanib Using LC-Q-TOF-MS/MS and NMR: An In Silico Approach for Degradation and Toxicity Prediction.
第一作者:
Nadeem,Shaikh
第一单位:
Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad, Telangana, India.
作者:
医学主题词
串联质谱法(Tandem Mass Spectrometry);喹啉类(Quinolines);磁共振波谱学(Magnetic Resonance Spectroscopy);色谱法, 高压液相(Chromatography, High Pressure Liquid);苯脲化合物(Phenylurea Compounds);计算机模拟(Computer Simulation);光解(Photolysis);水解作用(Hydrolysis);药物稳定性(Drug Stability);动物(Animals);色谱法, 液相(Chromatography, Liquid)
DOI
10.1002/rcm.10167
PMID
41243700
发布时间
2025-11-17
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