换一批Valproic acid-induced placental toxicity: mechanistic insights and the therapeutic potential of bioactive folates.
第一作者：
Numra,Shehzadi
第一单位：
Department of Biomedicine, Atta-Ur-Rahman School of Applied Biosciences, National University of Sciences & Technology, Islamabad, Pakistan.
作者：
关键词
5-Methyltetrahydrofolate (5-MTHF)Bioactive folatesEpigenetic regulationFolate metabolismFolinic acid (Leucovorin)Inflammatory cytokinesMethionine synthase reductase (MTR)Neurodevelopmental protectionOxidative stressPlacental toxicityPregnancy and antiepileptic drugsRat placenta modelTeratogenicityVEGF/angiogenesisValproic acid
医学主题词
动物(Animals);女(雌)性(Female);丙戊酸(Valproic Acid);妊娠(Pregnancy);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);胎盘(Placenta);抗惊厥药(Anticonvulsants);醛氢叶酸(Leucovorin);氧化性应激(Oxidative Stress);大鼠(Rats);四氢叶酸盐类(Tetrahydrofolates)
DOI
10.1007/s00210-025-04798-1
PMID
41251752
发布时间
2026-04-14
- 浏览0
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
