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Effective alternative strategies to combat challenges associated with MDR bacterial infections: Drug repurposing, role of artificial intelligence, and novel therapeutic options.

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第一作者： Sayed E,El-Sayed

第一单位： Department of Microbiology and Immunology, Faculty of Pharmacy, Ahram Canadian University, Sixth of October City, Giza 12451, Egypt. Electronic address: Sayed.emad@acu.Edu.eg.

作者： Sayed E,El-Sayed ^[1] ; Albeir A,Messiha ^[2] ; Mai,Zafer ^[3]

作者单位： Department of Microbiology and Immunology, Faculty of Pharmacy, Ahram Canadian University, Sixth of October City, Giza 12451, Egypt. Electronic address: Sayed.emad@acu.Edu.eg. ^[1] Department of Inpatient Pharmacy, Viginia Hospital Center, Arlington, VA 22205, USA. Electronic address: messiha@vhchealth.org. ^[2] Department of Microbiology and Immunology, Faculty of Pharmacy, Ahram Canadian University, Sixth of October City, Giza 12451, Egypt. Electronic address: maizafer@acu.edu.eg. ^[3]

关键词 Antimicrobial peptides (AMPs)Antimicrobial resistance (AMR)Artificial intelligence (AI)Bacterial secondary metabolites Bacteriophage therapy Drug repurposing Monoclonal antibodies Multitargeted drugs, Nanoparticles (NPs)Non-thermal plasma (NTP)

医学主题词人类(Humans);药物重新定位(Drug Repositioning);人工智能(Artificial Intelligence);细菌感染(Bacterial Infections);抗药性, 多种, 细菌(Drug Resistance, Multiple, Bacterial);抗菌药(Anti-Bacterial Agents);细菌(Bacteria)

DOI 10.1016/j.jiph.2025.103058

PMID 41274070

发布时间 2026-01-10

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准确一般字义偏差语意偏离译文作用小提交