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Single-Islet Proteomics Maps Pseudo-Temporal Islet Immune Responses and Dysfunction in Stage 1 Type 1 Diabetes.

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第一作者： Shane,Kelly

第一单位： Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA.

作者： Shane,Kelly ^[1] ; Soumyadeep,Sarkar ^[1] ; Sarai M,Williams ^[2] ; An D,Fu ^[3] ; Elizabeth A,Butterworth ^[3] ; Tyler J,Sagendorf ^[1] ; Lorenz A,Nierves ^[1] ; Yumi,Kwon ^[2] ; Xiaolu,Li ^[1] ; Vladislav A,Petyuk ^[1] ; Jing,Chen ^[3] ; Ernesto S,Nakayasu ^[1] ; Mark A,Atkinson ^[3] ; Rohit N,Kulkarni ^[4] ; Clayton E,Mathews ^[5] ; Ying,Zhu ^[6] ; Martha,Campbell-Thompson ^[3] ; Wei-Jun,Qian ^[1]

作者单位： Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA. ^[1] Environmental Molecular Sciences Division, Pacific Northwest National Laboratory, Richland, WA. ^[2] Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL. ^[3] Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA. ^[4] Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL.;Department of Infectious Disease and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL. ^[5] Environmental Molecular Sciences Division, Pacific Northwest National Laboratory, Richland, WA.;Present address: Department of Proteomic and Genomic Technologies, Genentech Inc., 1 DNA Way, South San Francisco, 94080, USA. ^[6]

DOI 10.1101/2025.11.10.687674

PMID 41292817

发布时间 2025-12-15

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Single-Islet Proteomics Maps Pseudo-Temporal Islet Immune Responses and Dysfunction in Stage 1 Type 1 Diabetes.

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Single-Islet Proteomics Maps Pseudo-Temporal Islet Immune Responses and Dysfunction in Stage 1 Type 1 Diabetes.

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