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首页> Signal transduction and targeted therapy> Preoperative pembrolizumab (anti-PD-1 antibody) combined with chemoradiotherapy for esophageal squamous cell carcinoma: a phase 1/2 trial (PALACE-2).

Preoperative pembrolizumab (anti-PD-1 antibody) combined with chemoradiotherapy for esophageal squamous cell carcinoma: a phase 1/2 trial (PALACE-2).

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第一作者： Chengqiang,Li
第一单位： Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
作者： Chengqiang,Li [1] ; Yichao,Han [1] ; Shengguang,Zhao [2] ; Xiaozheng,Kang [3] ; Yuyan,Zheng [1] ; Yuqin,Cao [1] ; Yan,Yan [1] ; Liqiang,Shi [1] ; Xipeng,Wang [1] ; Tong,Lu [1] ; Guowen,Zou [4] ; Huan,Li [2] ; Jiaming,Che [1] ; Jie,Xiang [1] ; Lianggang,Zhu [1] ; Junbiao,Hang [1] ; Yajie,Zhang [1] ; Runsen,Jin [1] ; Dingpei,Han [1] ; Xueyu,Chen [1] ; Hui,Jing [1] ; Wei,Guo [1] ; Zenghui,Cheng [5] ; Liqin,Zhao [6] ; Xiaoyan,Chen [7] ; Bentong,Yu [4] ; Jian,Li [8] ; Bin,Li [9] ; Yin,Li [10] ; Hecheng,Li [11]
作者单位： Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [1] Department of Radiotherapy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [2] Section of Esophageal and Mediastinal Oncology, Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. [3] Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Jiangxi, China. [4] Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [5] Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [6] Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [7] Clinical Research Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [8] Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Respiratory and Critical Care Medicine of Ruijin Hospital, Department of Thoracic Surgery of Ruijin Hospital, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. binli@shsmu.edu.cn. [9] Section of Esophageal and Mediastinal Oncology, Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. liyin@cicams.ac.cn. [10] Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lihecheng2000@hotmail.com. [11]
医学主题词 成年人(Adult);老年人(Aged);动物(Animals);女(雌)性(Female);人类(Humans);男(雄)性(Male);小鼠(Mice);中年人(Middle Aged);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);食管肿瘤(Esophageal Neoplasms);白细胞介素6(Interleukin-6);肿瘤辅助疗法(Neoadjuvant Therapy);紫杉酚(Paclitaxel);肿瘤微环境(Tumor Microenvironment)
DOI 10.1038/s41392-025-02477-4
PMID 41309527
发布时间 2025-12-18
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Signal transduction and targeted therapy

Signal transduction and targeted therapy

2025年10卷1期

386页

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