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Engineering ω-transaminase for efficient dihydroxyacetone transamination in serinol biosynthesis starting from methanol.

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第一作者： Ya,Wu

第一单位： Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan, 430079, China.

作者： Ya,Wu ^[1] ; Chonghao,Guo ^[2] ; Lizhen,Deng ^[2] ; Derui,Zhang ^[2] ; Yutong,Bie ^[2] ; Yuxin,He ^[2] ; Gen,Lu ^[2] ; Shewei,Hu ^[3] ; Ruiqi,Zeng ^[2] ; Zeyang,Li ^[2] ; Xudong,Xu ^[1] ; Longjiang,Yu ^[2]

作者单位： Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, 152 Luoyu Road, Wuhan, 430079, China. ^[1] Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, 430074, China. ^[2] Department of Biology and Food Engineering, Bozhou University, Bozhou, 236800, China. ^[3]

关键词 C1 biomanufacturing Epistasis analysis Molecular simulation Multienzyme cascade catalysis Serinol Transaminase engineering

DOI 10.1016/j.synbio.2025.11.004

PMID 41333073

发布时间 2025-12-05

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Synthetic and systems biotechnology

2026年12卷

71-81页

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Engineering ω-transaminase for efficient dihydroxyacetone transamination in serinol biosynthesis starting from methanol.

Synthetic and systems biotechnology

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Engineering ω-transaminase for efficient dihydroxyacetone transamination in serinol biosynthesis starting from methanol.

Synthetic and systems biotechnology

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Synthetic and systems biotechnology

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