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Screening telomere-related genes to predict prognosis, immunotherapy response, and drug sensitivity in esophageal cancer using a machine learning approach.

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第一作者： Shuang,Li

第一单位： Department of Cardiothoracic Surgery, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China.;Department of Cardiothoracic Surgery, People's Hospital Affiliated to Jiangsu University, Zhenjiang, 212000, China.

作者： Shuang,Li ^[1] ; Chen,Fang ^[2] ; Zheng,Tao ^[2] ; Wei,Jiang ^[2] ; Jingfeng,Zhu ^[3] ; Xiaojun,Yu ^[4] ; Haitao,Ma ^[5]

作者单位： Department of Cardiothoracic Surgery, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China.;Department of Cardiothoracic Surgery, People's Hospital Affiliated to Jiangsu University, Zhenjiang, 212000, China. ^[1] Department of Cardiothoracic Surgery, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China. ^[2] Department of Cardiothoracic Surgery, People's Hospital Affiliated to Jiangsu University, Zhenjiang, 212000, China. ^[3] Department of Cardiothoracic Surgery, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China. 18362738721@163.com. ^[4] Department of Cardiothoracic Surgery, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China. mht7403@163.com.;Department of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, 215000, China. mht7403@163.com. ^[5]

关键词 Esophageal cancer Gene signature Immune infiltration Prognosis Telomere

医学主题词端粒(Telomere);免疫疗法(Immunotherapy);食管肿瘤(Esophageal Neoplasms);人类(Humans);预后(Prognosis);计算生物学(Computational Biology)

DOI 10.1186/s13019-025-03727-w

PMID 41340128

发布时间 2026-03-12

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