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Prepuberty exposure to polystyrene nanoplastics induces cardiac inflammation through calcium overload-mediated ROS/JAK1/STAT3 signaling cascade.

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第一作者： Wei,Liu

第一单位： Department of Anesthesiology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 401122, China.

作者： Wei,Liu ^[1] ; Yang,Liu ^[2] ; Jin,Shi ^[3] ; Jiajin,Li ^[4] ; Gu,Li ^[4] ; Junjun,Quan ^[1] ; Weian,Zhao ^[5]

作者单位： Department of Anesthesiology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 401122, China. ^[1] Department of Anesthesiology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 401122, China; Department of Anesthesiology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Sichuan, 610072, China. ^[2] Department of Pediatrics, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China. ^[3] Department of Cardiology, Heart Center, Children's Hospital of Chongqing Medical University, Chongqing, 401122, China. ^[4] Department of Anesthesiology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 401122, China. Electronic address: 486313@hospital.cqmu.edu.cn. ^[5]

关键词 JAK1/STAT3 MAM PS-NPs ROS cardiac inflammation