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Piezoelectric nanoparticle-driven rhythmic ultrasound neuromodulation for treatment of early-stage Alzheimer's disease.

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第一作者： Xiaoxia,Li

第一单位： Department of Neurology, Affiliated Nanjing Drum Tower Hospital of Medical School, Nanjing University, Nanjing, 210009, China; Department of Polymer Science and Engineering, Key Laboratory of High-Performance Polymer Materials and Technology of MOE, State Key Laboratory of Analytical Chemistry for Life Science, Engineering Research Center of Photoresist Materials of MOE, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210023, China.

作者： Xiaoxia,Li ^[1] ; Sicheng,Yan ^[2] ; Mingding,Li ^[3] ; Renyuan,Liu ^[4] ; Qiangbing,Lu ^[2] ; Minghui,Lu ^[5] ; Feng,Bai ^[6] ; Qun-Dong,Shen ^[7]

作者单位： Department of Neurology, Affiliated Nanjing Drum Tower Hospital of Medical School, Nanjing University, Nanjing, 210009, China; Department of Polymer Science and Engineering, Key Laboratory of High-Performance Polymer Materials and Technology of MOE, State Key Laboratory of Analytical Chemistry for Life Science, Engineering Research Center of Photoresist Materials of MOE, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210023, China. ^[1] National Laboratory of Solid-State Microstructures, Department of Materials Science and Engineering, Nanjing University, Nanjing, 210093, China. ^[2] Department of Polymer Science and Engineering, Key Laboratory of High-Performance Polymer Materials and Technology of MOE, State Key Laboratory of Analytical Chemistry for Life Science, Engineering Research Center of Photoresist Materials of MOE, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210023, China; Key Laboratory of Materials & Surface Technology (MOE), School of Materials Science and Engineering, Xihua University, Chengdu, 610039, China. ^[3] Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210009, China. ^[4] National Laboratory of Solid-State Microstructures, Department of Materials Science and Engineering, Nanjing University, Nanjing, 210093, China; Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University, Nanjing, 210093, China. Electronic address: luminghui@nju.edu.cn. ^[5] Department of Neurology, Affiliated Nanjing Drum Tower Hospital of Medical School, Nanjing University, Nanjing, 210009, China. Electronic address: baifeng@njglyy.com. ^[6] Department of Neurology, Affiliated Nanjing Drum Tower Hospital of Medical School, Nanjing University, Nanjing, 210009, China; Department of Polymer Science and Engineering, Key Laboratory of High-Performance Polymer Materials and Technology of MOE, State Key Laboratory of Analytical Chemistry for Life Science, Engineering Research Center of Photoresist Materials of MOE, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing, 210023, China. Electronic address: qdshen@nju.edu.cn. ^[7]

关键词 Alzheimer's disease Low-intensity focused ultrasound Neural oscillation Piezoelectric nanoparticles Wireless rhythmic neuromodulation