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Proton versus photon radiotherapy for patients with oropharyngeal cancer in the USA: a multicentre, randomised, open-label, non-inferiority phase 3 trial.

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第一作者: Steven J,Frank
第一单位: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: sjfrank@mdanderson.org.
作者单位: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: sjfrank@mdanderson.org. [1] Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA. [2] Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [3] Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [4] Department of Radiation Oncology, Mayo Clinic-Arizona, Phoenix, AZ, USA. [5] Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA; Department of Radiation Oncology, School of Medicine, University of Maryland, Baltimore, MD, USA. [6] Mayo Clinic-Rochester, Rochester, MN, USA. [7] Department of Radiation Oncology, School of Medicine, University of Maryland, Baltimore, MD, USA. [8] New York Proton Center-Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. [9] Department of Radiation Oncology, University of Washington, Seattle, WA, USA. [10] Winship Cancer Institute of Emory University, Atlanta, GA, USA. [11] Department of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA. [12] Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. [13] Northwestern Medicine, Feinberg School of Medicine, Chicago, IL, USA. [14] Department of Radiation Oncology, University of Oklahoma Health Sciences, Oklahoma City, OK, USA. [15] McLaren Proton Therapy Center, Karmanos Cancer Center, Detroit, MI, USA. [16] Inova Radiation Oncology and Mather Proton Therapy Center, Schar Cancer Institute. Fairfax, VA, USA. [17] Willis-Knighton Cancer Center, Shreveport, LA, USA. [18] University of Florida Health Proton Institute, Jacksonville, FL, USA. [19] Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA. [20] Department of Thoracic-Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [21] Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [22] Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [23] Department of Anatomical Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [24]
DOI 10.1016/S0140-6736(25)01962-2
PMID 41391462
发布时间 2026-03-12
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Lancet (London, England)

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