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FFF as a microfluidic platform for the streamlined optimization of ready-to-use nanozyme-labelled probes to enable robust and ultra-sensitive chemiluminescent bioassays.

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第一作者： Luisa Stella,Dolci

第一单位： Department of Industrial Chemistry "Toso Montanari", University of Bologna, Via Piero Gobetti 85, Bologna, Italy.

作者： Luisa Stella,Dolci ^[1] ; Valentina,Marassi ^[2] ; Stefano,Giordani ^[2] ; Deborah,Pedone ^[3] ; Anna,Placci ^[2] ; Virginia,Rondinini ^[4] ; Erika,Scavetta ^[1] ; Pierluigi,Reschiglian ^[2] ; Mauro,Moglianetti ^[5] ; Pier Paolo,Pompa ^[6] ; Andrea,Zattoni ^[7] ; Barbara,Roda ^[8] ; Aldo,Roda ^[9]

作者单位： Department of Industrial Chemistry "Toso Montanari", University of Bologna, Via Piero Gobetti 85, Bologna, Italy. ^[1] Department of Chemistry G. Ciamician, University of Bologna, Italy; byFlow srl, Bologna, Italy; INBB, National Institute of Biostructure and Biosystems, Rome, Italy. ^[2] Nanobiointeractions & Nanodiagnostics, Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163, Genova, Italy. ^[3] Department of Chemistry G. Ciamician, University of Bologna, Italy. ^[4] Center for Cultural Heritage Technology CCHT, Istituto Italiano di Tecnologia (IIT), Via Torino 155, Venezia Mestre, 30172, Italy; Nanobiointeractions & Nanodiagnostics, Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163, Genova, Italy. ^[5] Nanobiointeractions & Nanodiagnostics, Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163, Genova, Italy; College of Optical Science and Engineering, Zhejiang University, Hangzhou, 310058, China. ^[6] Department of Chemistry G. Ciamician, University of Bologna, Italy; byFlow srl, Bologna, Italy; INBB, National Institute of Biostructure and Biosystems, Rome, Italy. Electronic address: andrea.zattoni@unibo.it. ^[7] Department of Chemistry G. Ciamician, University of Bologna, Italy; byFlow srl, Bologna, Italy; INBB, National Institute of Biostructure and Biosystems, Rome, Italy. Electronic address: barbara.roda@unibo.it. ^[8] Department of Chemistry G. Ciamician, University of Bologna, Italy; byFlow srl, Bologna, Italy. ^[9]

关键词 Chemiluminescent biosensors Hollow-fiber flow field-flow fractionation Isolation of conjugated ultrasmall Quality control of nanoenzymes Ultrasmall Pt nanoenzymes